The Crc and Hfq proteins of Pseudomonas putida cooperate in catabolite repression and formation of ribonucleic acid complexes with specific target motifs

R Moreno, S Hernández‐Arranz… - Environmental …, 2015 - Wiley Online Library
The Crc protein is a global regulator that has a key role in catabolite repression and
optimization of metabolism in Pseudomonads. Crc inhibits gene expression post …

Interplay between the catabolite repression control protein Crc, Hfq and RNA in Hfq-dependent translational regulation in Pseudomonas aeruginosa

E Sonnleitner, A Wulf, S Campagne, XY Pei… - Nucleic acids …, 2018 - academic.oup.com
In Pseudomonas aeruginosa the RNA chaperone Hfq and the c atabolite r epression c ontrol
protein (Crc) act as post-transcriptional regulators during carbon catabolite repression …

The Pseudomonas putida Crc global regulator is an RNA binding protein that inhibits translation of the AlkS transcriptional regulator

R Moreno, A Ruiz‐Manzano, L Yuste… - Molecular …, 2007 - Wiley Online Library
The Crc protein is a global regulator that controls the hierarchical assimilation of carbon
sources in Pseudomonads by inhibiting expression of several catabolic pathways. Crc does …

Regulation of Hfq by the RNA CrcZ in Pseudomonas aeruginosa Carbon Catabolite Repression

E Sonnleitner, U Bläsi - PLoS Genetics, 2014 - journals.plos.org
Carbon Catabolite repression (CCR) allows a fast adaptation of Bacteria to changing
nutrient supplies. The Pseudomonas aeruginosa (PAO1) catabolite repression control …

Stabilization of Hfq-mediated translational repression by the co-repressor Crc in Pseudomonas aeruginosa

EM Malecka, F Bassani, T Dendooven… - Nucleic Acids …, 2021 - academic.oup.com
In Pseudomonas aeruginosa the RNA chaperone Hfq and the c atabolite r epression c ontrol
protein (Crc) govern translation of numerous transcripts during carbon catabolite repression …

Effect of Crc and Hfq proteins on the transcription, processing, and stability of the Pseudomonas putida CrcZ sRNA

S Hernández-Arranz, D Sánchez-Hevia, F Rojo… - Rna, 2016 - rnajournal.cshlp.org
In Pseudomonas putida, the Hfq and Crc proteins regulate the expression of many genes in
response to nutritional and environmental cues, by binding to mRNAs that bear specific …

Two small RNAs, CrcY and CrcZ, act in concert to sequester the Crc global regulator in Pseudomonas putida, modulating catabolite repression

R Moreno, P Fonseca, F Rojo - Molecular microbiology, 2012 - Wiley Online Library
The Crc protein is a translational repressor that recognizes a specific target at some mRNAs,
controlling catabolite repression and co‐ordinating carbon metabolism in pseudomonads. In …

Pseudomonas putida growing at low temperature shows increased levels of CrcZ and CrcY sRNAs, leading to reduced Crc‐dependent catabolite repression

P Fonseca, R Moreno, F Rojo - Environmental microbiology, 2013 - Wiley Online Library
Summary The Crc protein of Pseudomonas inhibits the expression of genes involved in the
transport and assimilation of a number of non‐preferred carbon sources when preferred …

RNA mimicry, a decoy for regulatory proteins

S Marzi, P Romby - Molecular microbiology, 2012 - Wiley Online Library
Small non‐coding RNA molecules (sRNA) are key regulators participating in complex
networks, which adapt metabolism in response to environmental changes. In this issue of …

The Crc global regulator binds to an unpaired A-rich motif at the Pseudomonas putida alkS mRNA coding sequence and inhibits translation initiation

R Moreno, S Marzi, P Romby, F Rojo - Nucleic acids research, 2009 - academic.oup.com
Crc is a key global translational regulator in Pseudomonads that orchestrates the hierarchy
of induction of several catabolic pathways for amino acids, sugars, hydrocarbons or aromatic …