Distinctive Regulation of Carbapenem Susceptibility in Pseudomonas aeruginosa by Hfq

E Sonnleitner, P Pusic, MT Wolfinger… - Frontiers in microbiology, 2020 - frontiersin.org
Carbapenems are often the antibiotics of choice to combat life threatening infections caused
by the opportunistic human pathogen Pseudomonas aeruginosa. The outer membrane …

Translational regulation by Hfq–Crc assemblies emerges from polymorphic ribonucleoprotein folding

T Dendooven, E Sonnleitner, U Bläsi, BF Luisi - The EMBO Journal, 2023 - embopress.org
The widely occurring bacterial RNA chaperone Hfq is a key factor in the post‐transcriptional
control of hundreds of genes in Pseudomonas aeruginosa. How this broadly acting protein …

On the facultative requirement of the bacterial RNA chaperone, Hfq

A Jousselin, L Metzinger, B Felden - Trends in microbiology, 2009 - cell.com
The pleiotropic post-transcriptional regulator Hfq is an RNA chaperone that facilitates pairing
interactions between small regulatory RNAs (sRNAs) and their mRNA targets in several …

Integration of Signals through Crc and PtsN in Catabolite Repression of Pseudomonas putida TOL Plasmid pWW0

I Aranda-Olmedo, JL Ramos… - Applied and …, 2005 - Am Soc Microbiol
Toluene degradation in Pseudomonas putida KT2440 pWW0 plasmid is subjected to
catabolite repression. Pu and PS1 promoters of the pWW0 TOL plasmid are down-regulated …

[HTML][HTML] Structural basis for allosteric control of the transcription regulator CcpA by the phosphoprotein HPr-Ser46-P

MA Schumacher, GS Allen, M Diel, G Seidel, W Hillen… - Cell, 2004 - cell.com
Carbon catabolite repression (CCR) is one of the most fundamental environmental-sensing
mechanisms in bacteria and imparts competitive advantage by establishing priorities in …

Temporal evolution of master regulator Crp identifies pyrimidines as catabolite modulator factors

I Lauritsen, PO Frendorf, S Capucci, SAH Heyde… - Nature …, 2021 - nature.com
The evolution of microorganisms often involves changes of unclear relevance, such as
transient phenotypes and sequential development of multiple adaptive mutations in hotspot …

Catabolism of phenylalanine by Pseudomonas putida: the NtrC-family PhhR regulator binds to two sites upstream from the phhA gene and stimulates transcription …

MC Herrera, JL Ramos - Journal of molecular biology, 2007 - Elsevier
Pseudomonas putida uses l-phenylalanine as the sole nitrogen source for growth by
converting l-phenylalanine to l-tyrosine, which acts as a donor of the amino group. This …

Translational regulation by bacterial small RNAs via an unusual Hfq-dependent mechanism

MS Azam, CK Vanderpool - Nucleic acids research, 2018 - academic.oup.com
In bacteria, the canonical mechanism of translational repression by small RNAs (sRNAs)
involves sRNA-mRNA base pairing that occludes the ribosome binding site (RBS), directly …

Role of a local transcription factor in governing cellular carbon/nitrogen homeostasis in Pseudomonas fluorescens

N Naren, XX Zhang - Nucleic Acids Research, 2021 - academic.oup.com
Autoactivation of two-component systems (TCSs) can increase the sensitivity to signals but
inherently cause a delayed response. Here, we describe a unique negative feedback …

The Target for the Pseudomonas putida Crc Global Regulator in the Benzoate Degradation Pathway Is the BenR Transcriptional Regulator

R Moreno, F Rojo - Journal of bacteriology, 2008 - Am Soc Microbiol
Crc protein is a global regulator involved in catabolite repression control of several
pathways for the assimilation of carbon sources in pseudomonads when other preferred …