Beyond the “at risk mental state” concept: transitioning to transdiagnostic psychiatry
PD McGorry, JA Hartmann, R Spooner… - World …, 2018 - Wiley Online Library
The “at risk mental state” for psychosis approach has been a catalytic, highly productive
research paradigm over the last 25 years. In this paper we review that paradigm and …
research paradigm over the last 25 years. In this paper we review that paradigm and …
A critique of the “ultra‐high risk” and “transition” paradigm
J Van Os, S Guloksuz - World Psychiatry, 2017 - Wiley Online Library
The transdiagnostic expression of psychotic experiences in common mental disorder
(anxiety/depression/substance use disorder) is associated with a poorer prognosis, and a …
(anxiety/depression/substance use disorder) is associated with a poorer prognosis, and a …
[HTML][HTML] Pluripotential risk and clinical staging: theoretical considerations and preliminary data from a transdiagnostic risk identification approach
JA Hartmann, PD McGorry, L Destree… - Frontiers in …, 2021 - frontiersin.org
Most psychiatric disorders develop during adolescence and young adulthood and are
preceded by a phase during which attenuated or episodic symptoms and functional decline …
preceded by a phase during which attenuated or episodic symptoms and functional decline …
Broad clinical high‐risk mental state (CHARMS): Methodology of a cohort study validating criteria for pluripotent risk
JA Hartmann, B Nelson, R Spooner… - Early Intervention in …, 2019 - Wiley Online Library
Aim The development of the ultra‐high risk (UHR) criteria for psychosis created a new
paradigm for the prevention research in psychiatry. Since (1) prevention research faces the …
paradigm for the prevention research in psychiatry. Since (1) prevention research faces the …
Prevalence of non-psychotic disorders in ultra-high risk individuals and transition to psychosis: a systematic review
Despite the growing interest in the prodromes of psychosis, the proper identification of those
Ultra High Risk (UHR) subjects who will convert to psychosis remains an unresolved issue. It …
Ultra High Risk (UHR) subjects who will convert to psychosis remains an unresolved issue. It …
The psychosis high-risk state: a comprehensive state-of-the-art review
Context During the past 2 decades, a major transition in the clinical characterization of
psychotic disorders has occurred. The construct of a clinical high-risk (HR) state for …
psychotic disorders has occurred. The construct of a clinical high-risk (HR) state for …
High remission rates from an initial ultra-high risk state for psychosis
AE Simon, D Umbricht - Schizophrenia research, 2010 - Elsevier
OBJECTIVE: To investigate the proportion of patients among subjects initially identified as
fulfilling the ultra-high risk (UHR) criteria for psychosis using the Scale of Prodromal …
fulfilling the ultra-high risk (UHR) criteria for psychosis using the Scale of Prodromal …
Long-term follow-up of a group at ultra high risk (“prodromal”) for psychosis: the PACE 400 study
Importance The ultra high-risk (UHR) criteria were introduced to prospectively identify
patients at high risk of psychotic disorder. Although the short-term outcome of UHR patients …
patients at high risk of psychotic disorder. Although the short-term outcome of UHR patients …
Transition and remission in adolescents at ultra-high risk for psychosis
TB Ziermans, PF Schothorst, M Sprong… - Schizophrenia …, 2011 - Elsevier
BACKGROUND: Future success of early intervention initiatives to prevent the onset of
psychosis will rely on the validity of methods to predict clinical outcome. Proper identification …
psychosis will rely on the validity of methods to predict clinical outcome. Proper identification …
Ultra high risk (UHR) for psychosis criteria: are there different levels of risk for transition to psychosis?
INTRODUCTION: The ultra high risk (UHR) for psychosis criteria have been validated in a
number of studies. However, it is not known whether particular UHR criteria (Attenuated …
number of studies. However, it is not known whether particular UHR criteria (Attenuated …