The autoimmune concept of multiple sclerosis

B Nicol, M Salou, DA Laplaud, H Wekerle - La Presse Médicale, 2015 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central
nervous system (CNS). With growing evidence for environmental and genetic factors, MS is …

Immunopathogenesis of multiple sclerosis

M Comabella, SJ Khoury - Clinical immunology, 2012 - Elsevier
Multiple sclerosis (MS) is a chronic disorder of the central nervous system characterized by
autoimmune inflammation, demyelination, and axonal damage. MS etiology remains …

The immune response in multiple sclerosis

S Rodríguez Murúa, MF Farez… - Annual Review of …, 2022 - annualreviews.org
Multiple sclerosis (MS) is a chronic autoimmune, inflammatory, and neurodegenerative
disease that affects the central nervous system (CNS). MS is characterized by immune …

New immunopathologic insights into multiple sclerosis

B Hemmer, B Kieseier, S Cepok… - Current neurology and …, 2003 - Springer
Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central
nervous system. Although the immune system seems to play an important role in the …

Multiple sclerosis: an immunologic perspective

JY Cui - Physical Medicine and Rehabilitation Clinics, 2005 - pmr.theclinics.com
Multiple sclerosis (MS) is a chronic recurrent inflammatory disorder of the central nervous
system (CNS). The precise cause of MS remains unknown, although immune dysregulation …

Immunologic pathogenesis of multiple sclerosis

MF Guo, N Ji, CG Ma - Neuroscience bulletin, 2008 - ncbi.nlm.nih.gov
Multiple sclerosis (MS) is an autoimmune disease. The etiology and pathogenesis of MS
remain unclear. At present, there are substantial evidences to support the hypothesis that …

The immunobiology of multiple sclerosis: an autoimmune disease of the central nervous system

P Conlon, JR Oksenberg, J Zhang, L Steinman - Neurobiology of disease, 1999 - Elsevier
Multiple sclerosis (MS) is an inflammatory, demyelinating disease involving the white matter
of the central nervous system. Worldwide, approximately 1 million individuals are afflicted …

Immunological differences between classical phenothypes of multiple sclerosis

P Iwanowski, J Losy - Journal of the neurological sciences, 2015 - Elsevier
Multiple sclerosis (MS), one of the most serious inflammatory and neurodegenerative
conditions, is characterized by variable clinical courses—relapsing–remitting (RRMS) …

Multiple sclerosis: an immunologic reassessment

PY Paterson - Journal of chronic diseases, 1973 - Elsevier
THE PURSUIT of the etiology of multiple sclerosis (MS) has accelerated in recent years,
nourished by new evidence implicating immunologic factors in pathogenesis of the disease …

Immunology of multiple sclerosis

R Martin - Blue Books of Practical Neurology, 2003 - Elsevier
Publisher Summary This chapter describes the immunology of multiple sclerosis (MS). MS is
the most common inflammatory demyelinating disease of the central nervous system (CNS) …