Oxidative stress (OS), an imbalance between free radical generation and antioxidant
defence, is recognized as a key factor in the pathogenesis of adverse pregnancy outcomes …

During pregnancy, the placenta is a site of active oxygen metabolism that continuously
generates oxidative stress (OS). Overproduction of reactive oxygen species and reactive …

Oxidative stress designates the state of imbalance between reactive oxygen species (ROS)
production and antioxidant levels. In a healthy placenta, there is an increase in ROS …

It has been widely known that oxidative stress disrupts the balance between reactive oxygen
species (ROS) and the antioxidant system in the body. During pregnancy, the physiological …

In normal pregnancies, the earliest stages of development take place in a low oxygen (O 2)
environment. This physiological hypoxia of the early gestational sac protects the developing …

Considerable evidence implicates oxidative stress in the pathophysiology of many
complications of human pregnancy, and this topic has now become a major focus of both …

The pathophysiological mechanism underlying pregnancy complications such as congenital
malformations, miscarriage, preeclampsia, or fetal growth restriction is not entirely known …

The most important function of the placenta is the exchange of nutrients and oxygen
between a mother and her fetus. To establish a healthy functioning placenta, placentation …

Oxidative stress is worldwide recognized as a fundamental component of the aging, a
process that begins before birth. There is a critical balance between free radical generation …

In cases of miscarriage, onset of the maternal blood flow to the placenta is precocious and
disorganized compared with this event in normal pregnancy. We sought to determine …