[HTML][HTML] Harmonization of Molecular Monitoring of CML Therapy in Europe–Perspective of Widespread Competence in BCR-ABL Quantification.

MC Müller, NCP Cross, P Erben, T Schenk, T Ernst… - Blood, 2009 - Elsevier
Abstract Abstract 2616 Poster Board II-592 Introduction: The high efficacy of standard
treatment of chronic myeloid leukemia (CML) with imatinib has prompted the need for …

Harmonization of molecular monitoring of CML therapy in Europe

MC Müller, NCP Cross, P Erben, T Schenk, B Hanfstein… - Leukemia, 2009 - nature.com
The high efficacy of the standard treatment of chronic myeloid leukemia (CML) with imatinib
has prompted the need for accurate methods to monitor response at levels below the …

[HTML][HTML] Equivalence of BCR-ABL Transcript Levels< 1% According to the International Scale with Complete Cytogenetic Response in Chronic Phase CML Patients.

M Lauseker, B Hanfstein, C Haferlach, S Schnittger… - Blood, 2012 - Elsevier
Abstract Abstract 2495 Introduction: Response to therapy in patients with chronic myeloid
leukemia (CML) is monitored by both cytogenetic assessment of bone marrow metaphases …

[HTML][HTML] Standardization of molecular monitoring of CML: results and recommendations from the European treatment and outcome study

HE White, M Salmon, F Albano, CSA Andersen… - Leukemia, 2022 - nature.com
Standardized monitoring of BCR:: ABL1 mRNA levels is essential for the management of
chronic myeloid leukemia (CML) patients. From 2016 to 2021 the European Treatment and …

Stability of conversion factors for BCR-ABL monitoring-–implications for the frequency of validation rounds

MC Müller, U Munjal, P Erben, T Lion… - 2010 - ashpublications.org
Abstract Abstract 893 Introduction: A European collaborative harmonization study involving
61 laboratories is being conducted under the auspices of the European Treatment and …

Monitoring the response and course of chronic myeloid leukemia in the modern era of BCR-ABL tyrosine kinase inhibitors: practical advice on the use and …

H Kantarjian, C Schiffer, D Jones… - Blood, The Journal of …, 2008 - ashpublications.org
The management of hematologic malignancies, including chronic myeloid leukemia (CML),
chronic lymphocytic leukemia (CLL), and acute lymphocytic leukemia (ALL), has led the way …

International reporting scale of BCR-ABL1 fusion transcript in chronic myeloid leukemia: First report from India

P Balasubramanian, E Chendamarai, P Markose… - Acta …, 2012 - karger.com
Achieving a major molecular response (MMR) is an important predictor of progression-free
survival in chronic myeloid leukemia patients treated with imatinib. This requires accurate …

[HTML][HTML] Molecular measurement of BCR-ABL transcript variations in chronic myeloid leukemia patients in cytogenetic remission

M Serpa, SS Sanabani, PE Dorliac-Llacer, M Conchon… - BMC Hematology, 2010 - Springer
Background The monitoring of BCR-ABL transcript levels by real-time quantitative
polymerase chain reaction (RT-qPCR) has become important to assess minimal residual …

Rationale for the recommendations for harmonizing current methodology for detecting BCR-ABL transcripts in patients with chronic myeloid leukaemia

S Branford, NCP Cross, A Hochhaus, J Radich… - Leukemia, 2006 - nature.com
Molecular monitoring for patients with chronic myeloid leukaemia (CML) has become an
important practice in the era of imatinib therapy. For successful widespread introduction into …

Comparison of molecular responses based on BCR-ABL1%IS results from an in-house TaqMan-based qPCR versus Xpert® assay in CML patients on tyrosine …

N Boeckx, CV Laer, JD Roover, B Wilmsen… - Acta Clinica …, 2015 - Taylor & Francis
Abstract Objectives: Tyrosine kinase inhibitors (TKIs) have drastically changed the prospects
for chronic myeloid leukemia (CML) patients. The European LeukemiaNet (ELN) …