Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host
response to infection. Recently was been found that pyroptosis is a unique form of …

Sepsis, a life-threatening organ dysfunction caused by a dysregulated host response to
infection, is a leading cause of death in intensive care units. The development of sepsis …

Pyroptosis is a caspase-1 or caspase-4/5/11-dependent programmed cell death associated
with inflammation, which is initiated by inflammasomes or cytosolic LPS in innate immunity …

Sepsis is recognized as a life-threatening organ dysfunctional disease that is caused by
dysregulated host responses to infection. Up to now, sepsis still remains a dominant cause …

Immune cells and skin and mucosal epithelial cells recognize invasive microbes and other
signs of danger to sound alarms that recruit responder cells and initiate an immediate …

Inflammation is a defense mechanism that can protect the host against microbe invasion. A
proper inflammatory response can maintain homeostasis, but continuous inflammation can …

Programmed cell deaths are pathways involving cells playing an active role in their own
destruction. Depending on the signaling system of the process, programmed cell death can …

Sepsis is defined as a life‐threatening disease involving multiple organ dysfunction caused
by dysregulated host responses to infection. To date, sepsis remains a dominant cause of …

Pyroptosis, a type of programmed cell death mediated by gasdermin, is characterized by the
swelling and rupture of cells, release of cellular contents and a strong inflammatory …

Pyroptosis is a programmed and inflammatory cell death initiated by inflammasome. During
pyroptosis, cytosolic pattern recognition receptors, apoptosis-associated speck-like protein …