The promoter activity of yeast genes can depend on lysine 56 (K56) acetylation of histone
H3. This modification of H3 is performed by lysine acetylase Rtt109 acting in concert with …

RNA polymerase II initiates from low complexity sequences so cells must reliably
distinguish" real" from" cryptic" promoters and maintain fidelity to the former. Further, this …

De novo chromatin assembly into regularly spaced nucleosomal arrays is essential for
eukaryotic genome maintenance and inheritance. The Anti-Silencing Function 1 protein …

Abstract Anti-silencing function 1 (ASF1) is an evolutionarily conserved histone H3–H4
chaperone involved in the assembly/disassembly of nucleosome and histone modification …

The orderly deposition of histones onto DNA is mediated by conserved assembly
complexes, including chromatin assembly factor-1 (CAF-1) and the Hir proteins [1–4]. CAF-1 …

Background The YEATS domain is a highly conserved protein structure that interacts with
acetylated and crotonylated lysine residues in N-terminal tails of histones. The budding …

Acetylation within the globular core domain of histone H3 on lysine 56 (H3K56) has recently
been shown to have a critical role in packaging DNA into chromatin following DNA …

Background: Position-dependent gene silencing in yeast involves many factors, including
the four HIR genes and nucleosome assembly proteins Asf1p and chromatin assembly …

The SAS2 gene is involved in transcriptional silencing in Saccharomyces cerevisiae. Based
on its primary sequence, the Sas2 protein is predicted to be a member of the MYST family of …

In S phase, duplicating and assembling the whole genome into chromatin requires
upregulation of replicative histone gene expression. Here, we explored how histone …