Preparation of superparamagnetic iron oxide/doxorubicin loaded chitosan nanoparticles as a promising glioblastoma theranostic tool

L Gholami, M Tafaghodi, B Abbasi… - Journal of cellular …, 2019 - Wiley Online Library
Theranostic nanoparticles (NPs) are promising for opening new windows toward
personalized disease management. Using a single particle capable of both diagnosis and …

Targeting experimental orthotopic glioblastoma with chitosan-based superparamagnetic iron oxide nanoparticles (CS-DX-SPIONs)

M Shevtsov, B Nikolaev, Y Marchenko… - International Journal …, 2018 - Taylor & Francis
Background Glioblastoma is the most devastating primary brain tumor of the central nervous
system in adults. Magnetic nanocarriers may help not only for a targeted delivery of …

Doxorubicin and indocyanine green loaded superparamagnetic iron oxide nanoparticles with PEGylated phospholipid coating for magnetic resonance with …

C Shen, X Wang, Z Zheng, C Gao, X Chen… - International Journal …, 2019 - Taylor & Francis
Background Glioma represents the most common malignant brain tumor. Outcomes of
surgical resection are often unsatisfactory due to low sensitivity or resolution of imaging …

Doxorubicin-loaded iron oxide nanoparticles for glioblastoma therapy: A combinational approach for enhanced delivery of nanoparticles

M Norouzi, V Yathindranath, JA Thliveris, BM Kopec… - Scientific reports, 2020 - nature.com
Although doxorubicin (DOX) is an effective anti-cancer drug with cytotoxicity in a variety of
different tumors, its effectiveness in treating glioblastoma multiforme (GBM) is constrained by …

SPION and doxorubicin-loaded polymeric nanocarriers for glioblastoma theranostics

E Luque-Michel, L Lemaire… - Drug Delivery and …, 2021 - Springer
Glioma is a type of cancer with a very poor prognosis with a survival of around 15 months in
the case of glioblastoma multiforme (GBM). In order to advance in personalized medicine …

Evaluation of chitosan derivative microparticles encapsulating superparamagnetic iron oxide and doxorubicin as a pH-sensitive delivery carrier in hepatic carcinoma …

MY Bai, SL Tang, MH Chuang, TY Wang… - Frontiers in …, 2018 - frontiersin.org
We developed a novel, pH-sensitive drug delivery microparticle based on N-palmitoyl
chitosan (NPCS) to transport the superparamagnetic iron oxide (SPIO) and anticancer drug …

Stable and efficient Paclitaxel nanoparticles for targeted glioblastoma therapy

Q Mu, M Jeon, MH Hsiao, VK Patton… - Advanced …, 2015 - Wiley Online Library
Development of efficient nanoparticles (NPs) for cancer therapy remains a challenge. NPs
are required to have high stability, uniform size, sufficient drug loading, targeting capability …

Chitosan‐coated superparamagnetic iron oxide nanoparticles for doxorubicin delivery: synthesis and anticancer effect against human ovarian cancer cells

A Javid, S Ahmadian, AA Saboury… - Chemical biology & …, 2013 - Wiley Online Library
Doxorubicin‐loaded chitosan‐coated superparamagnetic iron oxide nanoparticles (Fe3O4;
SPIO‐NP s) were prepared by coprecipitation and emulsification cross‐linking method and …

Evaluation of toxicity and neural uptake in vitro and in vivo of superparamagnetic iron oxide nanoparticles

MK Khalid, M Asad, P Henrich-Noack… - International journal of …, 2018 - mdpi.com
Superparamagnetic iron oxide nanoparticles (SPIO-NPs) have great potential to be used in
different pharmaceutical applications, due to their unique and versatile physical and …

Co-encapsulation of superparamagnetic nanoparticles and doxorubicin in PLGA nanocarriers: Development, characterization and in vitro antitumor efficacy in glioma …

E Luque-Michel, V Sebastian, A Larrea… - European Journal of …, 2019 - Elsevier
With a very poor prognosis and no clear etiology, glioma is the most aggressive cancer in
the brain. Thanks to its versatility, nanomedicine is a promising option to overcome the …