Aim Cellular CD81 is a well characterized hepatitis C virus (HCV) entry factor, while the
relevance of soluble exosomal CD81 in HCV pathogenesis is poorly defined. We performed …

CD81 protein has been shown to bind hepatitis C virus (HCV) envelope 2 (E2) glycoprotein
in vitro and may act as a (co) receptor for HCV. Regulation of CD81 expression by interferon …

Hepatitis C virus (HCV) entry is dependent on CD81. To investigate whether the CD81
sequence is a determinant of HCV host range, we expressed a panel of diverse CD81 …

Hepatitis C Virus (HCV) infection is a global public health problem affecting over 160 million
individuals worldwide. Its symptoms include chronic hepatitis, liver cirrhosis and …

Chronic hepatitis C virus (HCV) infection occurs in about 3 percent of the world's population
and is a major cause of liver disease. HCV infection is also associated with …

BACKGROUND: Chronic hepatitis B (HBV) and hepatitis C (HCV) patients have elevated
plasma levels of soluble CD14 (sCD14). We examined whether human hepatocytes …

Background/Aims: Association of hepatitis C virus (HCV) with increased autoantibodies,
mixed cryoglobulinaemia, non-Hodgkin's B-cell lymphoma and increased peripheral innate …

ABSTRACT CD81 has been described as a putative receptor for hepatitis C virus (HCV);
however, its role in HCV cell entry has not been characterized due to the lack of an efficient …

We previously demonstrated that hepatitis C virus (HCV) binds to human CD81 through the
E2 glycoprotein. Therefore, expression of the human CD81 molecule in transgenic mice was …

Hepatitis C virus (HCV) infection is one of the major causes of chronic liver disease in the
Western world affecting 1.8% of the American population and 170 million people worldwide …