Globally, millions of individuals are impacted by neurodegenerative disorders including
Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD) …

Background Ferroptosis, as a new form of cell death, is different from other cell deaths such
as autophagy or senescence. Ferroptosis involves in the pathophysiological progress of …

Ferroptosis is an iron-dependent regulated cell death driven by excessive lipid peroxidation.
Inflammation is one common and effective physiological event that protects against various …

Ischemic stroke poses a significant health risk due to its high rate of disability and mortality.
To address this problem, several therapeutic approaches have been proposed, including …

Background Spinal cord injury (SCI) is a traumatic injury to the central nervous system and
can cause lipid peroxidation in the spinal cord. Ferroptosis, an iron-dependent programmed …

Regulation of cell mortality for disease treatment has been the focus of research. Ferroptosis
is an iron-dependent regulated cell death whose mechanism has been extensively studied …

Ischemia–reperfusion (I/R) is a common pathological phenomenon that occurs in numerous
organs and diseases. It generally results from secondary damage caused by the recovery of …

Spinal cord injury (SCI) leads to secondary neuronal death, which severely impedes
recovery of motor function. Therefore, prevention of neuronal cell death after SCI is an …

Background Transcriptome-wide analysis of peripheral blood in post-traumatic stress
disorder (PTSD) indicates widespread changes in immune-related pathways and function …

Spinal cord ischemia/reperfusion injury (SCIRI) induced by artificial aortic occlusion for a
while during aortic surgery is a serious complication, leading to paraplegia and even death …