[HTML][HTML] Efficacy and safety of voxelotor in sickle cell disease: a systematic review
Introduction: Sickle cell disease (SCD) is caused by mutation of beta-globin chain alleles,
with the involvement of at least one sickle mutation. Sickling of red cells leads to hemolytic …
with the involvement of at least one sickle mutation. Sickling of red cells leads to hemolytic …
[HTML][HTML] S118: LONG-TERM SAFETY AND EFFICACY OF VOXELOTOR FOR PATIENTS WITH SICKLE CELL DISEASE: RESULTS FROM AN OPEN-LABEL …
Background: Sickle cell disease (SCD), a lifelong, inherited blood disorder, leads to sickle
hemoglobin (HbS) formation. HbS polymerization causes red blood cell sickling, leading to …
hemoglobin (HbS) formation. HbS polymerization causes red blood cell sickling, leading to …
Over 4 Years of Safety and Efficacy with Voxelotor Treatment for Patients with Sickle Cell Disease: Updated Results from an Open-Label Extension of the Phase 3 …
MO Achebe, HMA Hassab, S Al-Kindi, C Brown… - Blood, 2023 - Elsevier
Introduction: Sickle cell disease (SCD) is an inherited blood disorder caused by a
homozygous or compound heterozygous mutation in the hemoglobin (Hb) subunit β gene …
homozygous or compound heterozygous mutation in the hemoglobin (Hb) subunit β gene …
[HTML][HTML] Long-term safety and efficacy of voxelotor for patients with sickle cell disease: results from an open-label extension of the phase 3 HOPE trial
Background: Sickle cell disease (SCD) is a lifelong, inherited blood disorder, resulting from
a mutation in the hemoglobin (Hb) subunit β gene, that leads to sickle hemoglobin (HbS) …
a mutation in the hemoglobin (Hb) subunit β gene, that leads to sickle hemoglobin (HbS) …
Voxelotor for Sickle Cell Disease: Initial Report from the Real-world PROSPECT Study
N Shah, B Andemariam, HH Billett… - Journal of Sickle Cell …, 2024 - academic.oup.com
Background Sickle cell disease (SCD) is an inherited blood disorder in which sickle
hemoglobin (HbS) polymerization results in red blood cell sickling, which in turn can lead to …
hemoglobin (HbS) polymerization results in red blood cell sickling, which in turn can lead to …
A phase 1/2 ascending dose study and open-label extension study of voxelotor in patients with sickle cell disease
J Howard, CJ Hemmaway, P Telfer… - Blood, The Journal …, 2019 - ashpublications.org
New treatments directly targeting polymerization of sickle hemoglobin (HbS), the proximate
event in the pathophysiology of sickle cell disease (SCD), are needed to address the severe …
event in the pathophysiology of sickle cell disease (SCD), are needed to address the severe …
[HTML][HTML] Real-world experience of patients with sickle cell disease treated with voxelotor: a multicenter, retrospective study
B Andemariam, M Achebe, ELJ Clay, RA Drachtman… - Blood, 2021 - Elsevier
Background: Sickle cell disease (SCD) is an inherited systemic disorder in which sickle
hemoglobin (HbS) polymerization triggers red blood cell sickling, chronic hemolytic anemia …
hemoglobin (HbS) polymerization triggers red blood cell sickling, chronic hemolytic anemia …
[HTML][HTML] Efficacy and safety of voxelotor in adolescents and adults with sickle cell disease: HOPE trial 72-week analysis
J Howard, KI Ataga, RC Brown, M Achebe, V Nduba… - Blood, 2020 - Elsevier
Background: Sickle cell disease (SCD) is a lifelong, inherited disorder characterized by
mutations in the hemoglobin (Hb) subunit β gene that leads to the production of sickle …
mutations in the hemoglobin (Hb) subunit β gene that leads to the production of sickle …
[HTML][HTML] P1485: A MULTICENTER, RETROSPECTIVE STUDY ON REAL-WORLD EXPERIENCE OF PATIENTS WITH SICKLE CELL DISEASE TREATED WITH …
B Andemariam, M Idowu, N Shah, R Drachtman… - …, 2022 - journals.lww.com
Background: Sickle cell disease (SCD) is an inherited systemic disorder, with pathology
driven by polymerization of sickle hemoglobin (HbS). Voxelotor, a HbS polymerization …
driven by polymerization of sickle hemoglobin (HbS). Voxelotor, a HbS polymerization …
Real-World Experience of Individuals with Sickle Cell Disease Treated with Voxelotor: Initial Report from the Multicenter, Prospective Prospect Study
B Andemariam, HH Billett, WB Ershler, S Bergmann… - Blood, 2023 - Elsevier
Introduction: Sickle cell disease (SCD) is an inherited blood disorder in which sickle
hemoglobin (HbS) polymerization results in red blood cell sickling, which in turn leads to …
hemoglobin (HbS) polymerization results in red blood cell sickling, which in turn leads to …