[HTML][HTML] Metabolomics and age-related macular degeneration

CN Brown, BD Green, RB Thompson, AI Den Hollander… - Metabolites, 2018 - mdpi.com
Age-related macular degeneration (AMD) leads to irreversible visual loss, therefore, early
intervention is desirable, but due to its multifactorial nature, diagnosis of early disease might …

[HTML][HTML] Metabolomics in age-related macular degeneration: a systematic review

XW Hou, Y Wang, CW Pan - Investigative ophthalmology & …, 2020 - iovs.arvojournals.org
Purpose: Age-related macular degeneration (AMD) is one of the leading causes of
blindness among the elderly, and the exact pathogenesis of the AMD remains unclear. The …

[HTML][HTML] Metabolomics in serum of patients with non-advanced age-related macular degeneration reveals aberrations in the glutamine pathway

E Kersten, S Dammeier, S Ajana, JMM Groenewoud… - PloS one, 2019 - journals.plos.org
Age-related macular degeneration (AMD) is a common, progressive multifactorial vision-
threatening disease and many genetic and environmental risk factors have been identified …

[HTML][HTML] Human plasma metabolomics in age-related macular degeneration: meta-analysis of two cohorts

I Laíns, W Chung, RS Kelly, J Gil, M Marques, P Barreto… - Metabolites, 2019 - mdpi.com
The pathogenesis of age-related macular degeneration (AMD), a leading cause of blindness
worldwide, remains only partially understood. This has led to the current lack of accessible …

Human plasma metabolomics study across all stages of age-related macular degeneration identifies potential lipid biomarkers

I Laíns, RS Kelly, JB Miller, R Silva, DG Vavvas, IK Kim… - Ophthalmology, 2018 - Elsevier
Purpose To characterize the plasma metabolomic profile of patients with age-related
macular degeneration (AMD) using mass spectrometry (MS). Design Cross-sectional …

[HTML][HTML] Metabolomics in retinal diseases: an update

X Li, S Cai, Z He, J Reilly, Z Zeng, N Strang, X Shu - Biology, 2021 - mdpi.com
Simple Summary Visual loss and blindness caused by retinal disease has a significant
negative effect on the quality of life of many adults and children, and as a result has become …

Reprogramming the metabolome rescues retinal degeneration

KS Park, CL Xu, X Cui, SH Tsang - Cellular and Molecular Life Sciences, 2018 - Springer
Metabolomics studies in the context of ophthalmology have largely focused on identifying
metabolite concentrations that characterize specific retinal diseases. Studies involving mass …

[HTML][HTML] Plasma metabolomic profiles associated with three-year progression of age-related macular degeneration

I Lains, K Mendez, A Nigalye, R Katz, VP Douglas… - Metabolites, 2022 - mdpi.com
Plasma metabolomic profiles have been shown to be associated with age-related macular
degeneration (AMD) and its severity stages. However, all studies performed to date have …

[HTML][HTML] Human plasma metabolomics in age-related macular degeneration (AMD) using nuclear magnetic resonance spectroscopy

I Lains, D Duarte, AS Barros, AS Martins, J Gil… - PloS one, 2017 - journals.plos.org
Purpose To differentiate the plasma metabolomic profile of patients with age related macular
degeneration (AMD) from that of controls, by Nuclear Magnetic Resonance (NMR) …

[HTML][HTML] Integrating metabolomics, genomics, and disease pathways in age-related macular degeneration: the EYE-RISK consortium

IE Acar, L Lores-Motta, JM Colijn, MA Meester-Smoor… - Ophthalmology, 2020 - Elsevier
Purpose The current study aimed to identify metabolites associated with age-related
macular degeneration (AMD) by performing the largest metabolome association analysis in …