[HTML][HTML] Metabolomics and age-related macular degeneration
Age-related macular degeneration (AMD) leads to irreversible visual loss, therefore, early
intervention is desirable, but due to its multifactorial nature, diagnosis of early disease might …
intervention is desirable, but due to its multifactorial nature, diagnosis of early disease might …
[HTML][HTML] Metabolomics in age-related macular degeneration: a systematic review
XW Hou, Y Wang, CW Pan - Investigative ophthalmology & …, 2020 - iovs.arvojournals.org
Purpose: Age-related macular degeneration (AMD) is one of the leading causes of
blindness among the elderly, and the exact pathogenesis of the AMD remains unclear. The …
blindness among the elderly, and the exact pathogenesis of the AMD remains unclear. The …
[HTML][HTML] Metabolomics in serum of patients with non-advanced age-related macular degeneration reveals aberrations in the glutamine pathway
E Kersten, S Dammeier, S Ajana, JMM Groenewoud… - PloS one, 2019 - journals.plos.org
Age-related macular degeneration (AMD) is a common, progressive multifactorial vision-
threatening disease and many genetic and environmental risk factors have been identified …
threatening disease and many genetic and environmental risk factors have been identified …
[HTML][HTML] Human plasma metabolomics in age-related macular degeneration: meta-analysis of two cohorts
The pathogenesis of age-related macular degeneration (AMD), a leading cause of blindness
worldwide, remains only partially understood. This has led to the current lack of accessible …
worldwide, remains only partially understood. This has led to the current lack of accessible …
Human plasma metabolomics study across all stages of age-related macular degeneration identifies potential lipid biomarkers
Purpose To characterize the plasma metabolomic profile of patients with age-related
macular degeneration (AMD) using mass spectrometry (MS). Design Cross-sectional …
macular degeneration (AMD) using mass spectrometry (MS). Design Cross-sectional …
[HTML][HTML] Metabolomics in retinal diseases: an update
X Li, S Cai, Z He, J Reilly, Z Zeng, N Strang, X Shu - Biology, 2021 - mdpi.com
Simple Summary Visual loss and blindness caused by retinal disease has a significant
negative effect on the quality of life of many adults and children, and as a result has become …
negative effect on the quality of life of many adults and children, and as a result has become …
Reprogramming the metabolome rescues retinal degeneration
KS Park, CL Xu, X Cui, SH Tsang - Cellular and Molecular Life Sciences, 2018 - Springer
Metabolomics studies in the context of ophthalmology have largely focused on identifying
metabolite concentrations that characterize specific retinal diseases. Studies involving mass …
metabolite concentrations that characterize specific retinal diseases. Studies involving mass …
[HTML][HTML] Plasma metabolomic profiles associated with three-year progression of age-related macular degeneration
Plasma metabolomic profiles have been shown to be associated with age-related macular
degeneration (AMD) and its severity stages. However, all studies performed to date have …
degeneration (AMD) and its severity stages. However, all studies performed to date have …
[HTML][HTML] Human plasma metabolomics in age-related macular degeneration (AMD) using nuclear magnetic resonance spectroscopy
Purpose To differentiate the plasma metabolomic profile of patients with age related macular
degeneration (AMD) from that of controls, by Nuclear Magnetic Resonance (NMR) …
degeneration (AMD) from that of controls, by Nuclear Magnetic Resonance (NMR) …
[HTML][HTML] Integrating metabolomics, genomics, and disease pathways in age-related macular degeneration: the EYE-RISK consortium
IE Acar, L Lores-Motta, JM Colijn, MA Meester-Smoor… - Ophthalmology, 2020 - Elsevier
Purpose The current study aimed to identify metabolites associated with age-related
macular degeneration (AMD) by performing the largest metabolome association analysis in …
macular degeneration (AMD) by performing the largest metabolome association analysis in …