Nanoparticles (NPs) containing the hydrophilic drug salidroside (Sal) and the hydrophobic
drug tamoxifen (Tam) were prepared using a triblock copolymer poly (lactic-co-glycolic …

Tamoxifen (Tmx) embedded poly (lactic-co-glycolic acid)(PLGA) nanoparticles (PLGA-Tmx)
is prepared to evaluate its better DNA cleavage potential, cytotoxicity using Dalton's …

Multidrug-resistant breast cancers have limited and ineffective clinical treatment options.
This study aimed to develop PLGA nanoparticles containing a synergistic combination of …

Purpose Conventional chemotherapy is hampered by the presence of breast cancer stem
cells (BCSCs). It is crucial to eradicating both the bulky breast cancer cells and BCSCs …

Nanoparticulate delivery systems have been noticed for chemotherapeutical delivery due to
their ability in controlling the drug release and reducing the side effect. These systems could …

Purpose Letrozole (LTZ), an aromatase inhibitor with poor aqueous solubility, is used as the
first line treatment for hormonal sensitive breast cancer in postmenopausal women. The …

β-Sitosterol (β-Sit) is a dietary phytosterol with demonstrated anticancer activity against a
panel of cancers, but its poor solubility in water limits its bioavailability and therapeutic …

Purpose This study was carried out to formulate poly (lactide-co-glycolide)(PLGA)
nanoparticles using a quaternary ammonium salt didodecyl dimethylammonium bromide …

Background: Tamoxifen is widely used for the treatment of estrogen receptor-positive breast
cancer. However, it is associated with severe side effects of cancerous proliferation on the …

Improved therapeutic effects can be achieved by the delivery of combination of drugs
through multifunctional cell targeted nanocarrier systems. The present investigation reports …