Selenium as an essential micronutrient: roles in cell cycle and apoptosis

H Zeng - Molecules, 2009 - mdpi.com
Selenium is an essential trace element for humans and animals, and selenium deficiency is
associated with several disease conditions such as immune impairment. In addition …

Apoptosis is a critical cellular event in cancer chemoprevention and chemotherapy by selenium compounds

R Sinha, K El-Bayoumy - Current cancer drug targets, 2004 - ingentaconnect.com
Epidemiological studies, preclinical investigations and clinical intervention trials support the
role of selenium compounds as potent cancer chemopreventive agents; the dose and the …

Molecular targets for selenium in cancer prevention

YS Kim, J Milner - Selenium and Cancer, 2001 - taylorfrancis.com
Mounting evidence reveals that selenium is a dietary constituent with anticarcinogenic and
antitumorigenic properties. Various forms of selenium appear to be effective in bringing …

Selenium compounds and apoptotic modulation: a new perspective in cancer therapy

C Sanmartin, D Plano, JA Palop - Mini reviews in medicinal …, 2008 - ingentaconnect.com
Recent epidemiological studies have demonstrated that selenium may be an effective
chemopreventive and anticancer agent with a broad spectrum against several human …

[HTML][HTML] Selenite and selenomethionine promote HL-60 cell cycle progression

H Zeng - The Journal of nutrition, 2002 - Elsevier
The essential role of selenium (Se) in nutrition is well established. The elucidation of the
mechanisms by which selenium regulates the cell cycle can lead to a better understanding …

Selenium and the regulation of cell signaling, growth, and survival: molecular and mechanistic aspects

RC McKenzie, JR Arthur, GJ Beckett - Antioxidants and Redox …, 2002 - liebertpub.com
In the past 30 years, it has been recognized that dietary selenium (Se) is essential for the
normal function of many of the systems of the body. Furthermore, low Se intake can have …

Selenium as an anticancer nutrient: roles in cell proliferation and tumor cell invasion

H Zeng, GF Combs Jr - The Journal of nutritional biochemistry, 2008 - Elsevier
Selenium is an essential dietary component for animals including humans, and there is
increasing evidence for the efficacy of certain forms of selenium as cancer-chemopreventive …

Selenium and selenocysteine: roles in cancer, health, and development

DL Hatfield, PA Tsuji, BA Carlson… - Trends in biochemical …, 2014 - cell.com
The many biological and biomedical effects of selenium are relatively unknown outside the
selenium field. This fascinating element, initially described as a toxin, was subsequently …

Understanding the redox biology of selenium in the search of targeted cancer therapies

JM Stolwijk, R Garje, JC Sieren, GR Buettner… - Antioxidants, 2020 - mdpi.com
Selenium (Se) is an essential trace nutrient required for optimal human health. It has long
been suggested that selenium has anti-cancer properties. However, clinical trials have …

Selenium and selenoproteins in health

F Zhang, X Li, Y Wei - Biomolecules, 2023 - mdpi.com
Selenium is a trace mineral that is essential for health. After being obtained from food and
taken up by the liver, selenium performs various physiological functions in the body in the …