[HTML][HTML] Molecular characterization of the clinical and tumor immune microenvironment signature of 5-methylcytosine-related regulators in non-small cell lung cancer

T Liu, L Guo, G Liu, X Hu, X Li, J Zhang… - Frontiers in Cell and …, 2021 - frontiersin.org
Background: DNA methylation is an important epigenetic modification, among which 5-
methylcytosine methylation (5mC) is generally associated with tumorigenesis. Nonetheless …

[HTML][HTML] M5C regulator-mediated methylation modification patterns and tumor microenvironment infiltration characterization in lung adenocarcinoma

H Chen, XL Ge, ZY Zhang, M Liu, RY Wu… - Translational Lung …, 2021 - ncbi.nlm.nih.gov
Background In recent years, immunotherapy has made great progress, and the regulatory
role of epigenetics has been verified. However, the role of 5-methylcytosine (m 5 C) in the …

Construction of a 5-methylcytosine-related molecular signature to inform the prognosis and immunotherapy of lung squamous cell carcinoma

R He, X Feng, K Yang, X Zhou, W Li… - Expert Review of …, 2022 - Taylor & Francis
Background Methylation of cytosine residues resulting in 5-methylcytosine (5-mC) is an
important epigenetic modification associated with tumorigenesis. The present study …

[HTML][HTML] 5-methylcytosine RNA methylation regulators affect prognosis and tumor microenvironment in lung adenocarcinoma

T Liu, X Hu, C Lin, X Shi, Y He, J Zhang… - Annals of translational …, 2022 - ncbi.nlm.nih.gov
Background Accumulating evidence has shown that 5-methylcytosinec (m5C) RNA
methylation plays an essential role in tumorigenesis. However, the roles of m5C regulators …

[HTML][HTML] m6A regulators featured by tumor immune microenvironment landscapes and correlated with immunotherapy in non-small cell lung cancer (NSCLC)

B Yuan, H Qin, J Zhang, M Zhang, Y Yang… - Frontiers in …, 2022 - frontiersin.org
Introduction Recent research has confirmed the critical role that epigenetic factors play in
regulating the immune response. Nonetheless, what role m6A methylation modification …

[HTML][HTML] m5C RNA methylation regulators predict prognosis and regulate the immune microenvironment in lung squamous cell carcinoma

J Pan, Z Huang, Y Xu - Frontiers in Oncology, 2021 - frontiersin.org
RNA methylation is a novel epigenetic modification that can be used to evaluate tumor
prognosis. However, the underlying mechanisms are unclear. This study aimed to …

[HTML][HTML] Correlation analysis of m6A-modified regulators with immune microenvironment infiltrating cells in lung adenocarcinoma

W Ye, T Huang - Plos one, 2022 - journals.plos.org
Object Recent studies have demonstrated the epigenetic regulation of immune responses.
However, the potential role of N6-methyladenosine methylation (m6A) in the tumor …

M6A regulator expression patterns predict the immune microenvironment and prognosis of non-small cell lung cancer

X Liu, C Ma, H Liu, Z Sun, J Luo - Journal of Cancer Research and …, 2022 - Springer
Background The m6A methylation modification is one of the most common mRNA
modifications, and involved in a variety of biological processes, such as cell death, cancer …

m6A Regulator-Mediated Methylation Modification Patterns and Characterisation of Tumour Microenvironment Infiltration in Non-Small Cell Lung Cancer

Y Fan, Y Zhou, M Lou, X Li, X Zhu… - Journal of Inflammation …, 2022 - Taylor & Francis
Purpose The role of RNA N6-methyladenosine (m6A) modification in the progression of
multiple tumours and the tumour microenvironment (TME) has been progressively …

Integrative analysis of m6A RNA methylation regulators and the tumor immune microenvironment in non‐small‐cell lung cancer

J Zhu, Y Jiang, T Wang, A Wu, T Zhou… - Disease …, 2022 - Wiley Online Library
Background. Non‐small‐cell lung cancer (NSCLC) is a major component of lung cancer and
is significantly correlated with poor prognosis. N6‐methyladenosine (m6A) RNA methylation …