Risperidone ameliorated Aβ1-42-induced cognitive and hippocampal synaptic impairments in mice
L Wu, X Feng, T Li, B Sun, MZ Khan, L He - Behavioural brain research, 2017 - Elsevier
Alzheimer's disease (AD) is a complex neurodegenerative disorder with cognitive
impairment and major neuropathologic hallmark of amyloid-beta (Aβ) peptides. Risperidone …
impairment and major neuropathologic hallmark of amyloid-beta (Aβ) peptides. Risperidone …
ERK and p38 inhibitors attenuate memory deficits and increase CREB phosphorylation and PGC-1α levels in Aβ-injected rats
In this study, we investigated the effect of intracerebroventricular administration of ERK and
p38 specific inhibitors, U0126 and PD169316, respectively, on learning and memory deficits …
p38 specific inhibitors, U0126 and PD169316, respectively, on learning and memory deficits …
[PDF][PDF] Effect of reserpine on the behavioral defects, Aβ-42 deposition and NGF metabolism in Tg2576 transgenic mouse model for Alzheimer's disease
J Go, SI Choi, JE Kim, YJ Lee, MH Kwak… - Journal of Life …, 2013 - researchgate.net
Reserpine, an anti-hypertensive drug, is able to positively modulate several phenotypes
associated with Aβ toxicity in a Caenorhabditis elegans model of Alzheimer's disease (AD) …
associated with Aβ toxicity in a Caenorhabditis elegans model of Alzheimer's disease (AD) …
The ameliorative effects and underlying mechanisms of dopamine D1-like receptor agonist SKF38393 on Aβ1–42-induced cognitive impairment
X Zang, ZY Cheng, Y Sun, N Hua, LH Zhu… - Progress in Neuro …, 2018 - Elsevier
Alzheimer's disease (AD) is an age-related neurodegenerative disease characterized by
extracellular amyloid plaques and intracellular neurofibrillary tangles. It is the most common …
extracellular amyloid plaques and intracellular neurofibrillary tangles. It is the most common …
Desipramine improves depression-like behavior and working memory by up-regulating p-CREB in Alzheimer's disease associated mice
DD Wang, J Li, LP Yu, MN Wu, LN Sun… - Journal of Integrative …, 2016 - World Scientific
Aggregation of amyloid β protein (A β) and progressive loss of memory are the main
characteristics of Alzheimer's disease (AD). It is noteworthy that approximately 40% of AD …
characteristics of Alzheimer's disease (AD). It is noteworthy that approximately 40% of AD …
SB203580 reverses memory deficits and depression-like behavior induced by microinjection of Aβ1–42 into hippocampus of mice
J Guo, L Chang, C Li, M Li, P Yan, Z Guo, C Wang… - Metabolic brain …, 2017 - Springer
A high co-morbidity between Alzheimer's disease (AD) and depression suggests there might
be similar mechanisms underlying the course of these diseases. Previous studies have …
be similar mechanisms underlying the course of these diseases. Previous studies have …
Protective effects of selegiline against amyloid beta‐induced anxiety‐like behavior and memory impairment
B Mohamadpour, N Mirazi, A Komaki… - Brain and …, 2024 - Wiley Online Library
Background Alzheimer's disease (AD) is a complex and common neurodegenerative
disorder. The present study aimed to investigate the potential effects of selegiline (SEL) on …
disorder. The present study aimed to investigate the potential effects of selegiline (SEL) on …
[HTML][HTML] The effect of resveratrol on beta amyloid-induced memory impairment involves inhibition of phosphodiesterase-4 related signaling
G Wang, L Chen, X Pan, J Chen, L Wang, W Wang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Resveratrol, a natural polyphenol found in red wine, has wide spectrum of pharmacological
properties including antioxidative and antiaging activities. Beta amyloid peptides (Aβ) are …
properties including antioxidative and antiaging activities. Beta amyloid peptides (Aβ) are …
Riluzole ameliorates learning and memory deficits in Aβ25-35-induced rat model of Alzheimer's disease and is independent of cholinoceptor activation
Z Mokhtari, T Baluchnejadmojarad, F Nikbakht… - Biomedicine & …, 2017 - Elsevier
Alzheimer's disease (AD) is a major global public health concern and social care problem
that is associated with learning, memory, and cognitive deficits. Riluzole is a glutamate …
that is associated with learning, memory, and cognitive deficits. Riluzole is a glutamate …
Salidroside attenuates beta amyloid-induced cognitive deficits via modulating oxidative stress and inflammatory mediators in rat hippocampus
J Zhang, Y Zhen, L Song, W Kong, T Shao, X Li… - Behavioural brain …, 2013 - Elsevier
Beta amyloid (Aβ)-induced oxidative stress and chronic inflammation in the brain are
considered to be responsible for the pathogenesis of Alzheimer's disease (AD). Salidroside …
considered to be responsible for the pathogenesis of Alzheimer's disease (AD). Salidroside …