MicroRNA-based biomarkers in the diagnosis and monitoring of therapeutic response in patients with depression

YY Xu, QH Xia, QR Xia, XL Zhang… - … disease and treatment, 2019 - Taylor & Francis
Depression is a debilitating mental illness that affects up to 120 million people worldwide; it
is currently determined based on subjective diagnostic schemes that are limited by high …

[HTML][HTML] microRNAs as biomarker in depression pathogenesis

Y Dwivedi - Annals of psychiatry and mental health, 2013 - ncbi.nlm.nih.gov
Major depressive disorder (MDD) is a major health concern with alarming rates of completed
suicide. Thus, it is important to understand the pathophysiology of this disorder. In addition …

Exploiting circulating MicroRNAs as biomarkers in psychiatric disorders

B Roy, Y Yoshino, L Allen, K Prall, G Schell… - Molecular diagnosis & …, 2020 - Springer
Non-invasive peripheral biomarkers play a significant role in both disease diagnosis and
progression. In the past few years, microRNA (miRNA) expression changes in circulating …

Emerging role of microRNAs in major depressive disorder: diagnosis and therapeutic implications

Y Dwivedi - Dialogues in clinical neuroscience, 2014 - Taylor & Francis
Major depressive disorder (MDD) is a major public health concern. Despite tremendous
advances, the pathogenic mechanisms associated with MDD are still unclear. Moreover, a …

Pathogenetic and therapeutic applications of microRNAs in major depressive disorder

Y Dwivedi - Progress in Neuro-Psychopharmacology and …, 2016 - Elsevier
As a class of noncoding RNAs, microRNAs (miRNAs) regulate gene expression by inhibiting
translation of messenger RNAs. These miRNAs have been shown to play a critical role in …

[HTML][HTML] MicroRNAs as critical biomarkers of major depressive disorder: a comprehensive perspective

MA Ortega, MA Alvarez-Mon, C García-Montero… - Biomedicines, 2021 - mdpi.com
Major Depressive Disorder (MDD) represents a major global health concern, a body-mind
malady of rising prevalence worldwide nowadays. The complex network of mechanisms …

[HTML][HTML] Uncovering the roles of microRNAs in major depressive disorder: from candidate diagnostic biomarkers to treatment response indicators

C Homorogan, D Nitusca, E Seclaman, V Enatescu… - Life, 2021 - mdpi.com
Major depressive disorder (MDD) is a recurrent debilitating illness that represents a major
health burden due to its increasing worldwide prevalence, unclear pathological mechanism …

Major depression and its treatment: microRNAs as peripheral biomarkers of diagnosis and treatment response

JP Lopez, A Kos, G Turecki - Current opinion in psychiatry, 2018 - journals.lww.com
In this review, we discuss the growing field, investigating peripheral miRNAs as potential
biomarkers of major depression and treatment response. A noninvasive and validated …

The important roles of microRNAs in depression: new research progress and future prospects

C Miao, J Chang - Journal of Molecular Medicine, 2021 - Springer
MicroRNAs (miRNAs) are non-encoding, single-stranded RNA molecules of about 22
nucleotides in length encoded by endogenous genes involved in posttranscriptional gene …

[HTML][HTML] MicroRNAs as diagnostic biomarkers and predictors of antidepressant response in major depressive disorder: a systematic review

BA Carneiro, LNF Guerreiro-Costa, D Lins-Silva… - Cureus, 2024 - ncbi.nlm.nih.gov
Despite the hardships of major depressive disorder (MDD), biomarkers for the diagnosis and
pharmacological management of this condition are lacking. MicroRNAs are epigenetic …