Role of oxidative stress in sulfur mustard-induced pulmonary injury and antioxidant protection

E Tahmasbpour, S Reza Emami, M Ghanei… - Inhalation …, 2015 - Taylor & Francis
Sulfur mustard (SM) is a potent alkylating agent that targets several organs, especially lung
tissue. Although pathological effects of SM have been widely considered, molecular and …

Free radical production and oxidative stress in lung tissue of patients exposed to sulfur mustard: an overview of cellular and molecular mechanisms

A Beigi Harchegani, E Tahmasbpour… - Chemical research in …, 2018 - ACS Publications
Sulfur mustard (SM) is a chemical alkylating compound that primary targets lung tissue. It
causes a wide variety of pathological effects in respiratory system such as chronic bronchitis …

Sulfur mustard-induced pulmonary injury: therapeutic approaches to mitigating toxicity

B Weinberger, JD Laskin, VR Sunil, PJ Sinko… - Pulmonary …, 2011 - Elsevier
Sulfur mustard (SM) is highly toxic to the lung inducing both acute and chronic effects
including upper and lower obstructive disease, airway inflammation, and acute respiratory …

Gene expression profile of oxidative stress and antioxidant defense in lung tissue of patients exposed to sulfur mustard

E Tahmasbpour, M Ghanei, A Qazvini, E Vahedi… - … /Genetic Toxicology and …, 2016 - Elsevier
Sulfur mustard (SM) is a potent alkylating agent that targets several organs, especially lung
tissue. Although pathological effects of SM on mustard lung have been widely considered …

Molecular and cellular mechanism of lung injuries due to exposure to sulfur mustard: a review

M Ghanei, AA Harandi - Inhalation toxicology, 2011 - Taylor & Francis
Sulfur mustard (SM), a potent chemical weapon agent, was used by Iraqi forces against
Iranian in the Iraq–Iran war (1981–1989). Chronic obstructive pulmonary disease (COPD) is …

Progressive lung injury, inflammation, and fibrosis in rats following inhalation of sulfur mustard

R Malaviya, EV Abramova, RC Rancourt… - Toxicological …, 2020 - academic.oup.com
Sulfur mustard (SM) inhalation causes debilitating pulmonary injury in humans which
progresses to fibrosis. Herein, we developed a rat model of SM toxicity which parallels …

Cellular and molecular mechanisms of acute exposure to sulfur mustard: a systematic review

MR Nourani, H Mahmoodzadeh Hosseini… - Journal of Receptors …, 2017 - Taylor & Francis
Context: Mustard gas (eg sulfur mustard (SM)) has been used as a chemical agent in
several battles and is still a potential worldwide menace. Besides local absorption …

Mechanism underlying acute lung injury due to sulfur mustard exposure in rats

Z Xiaoji, M Xiao, X Rui, C Haibo… - Toxicology and …, 2016 - journals.sagepub.com
Sulfur mustard (SM), a bifunctional alkylating agent that causes severe lung damage, is a
significant threat to both military and civilian populations. The mechanisms mediating the …

A review on proteomics analysis to reveal biological pathways and predictive proteins in sulfur mustard exposed patients: roles of inflammation and oxidative stress

H Borna, SH Hosseini Qale Noe… - Inhalation …, 2019 - Taylor & Francis
Sulfur mustard (SM) is a mutagenic compound that targets various organs. Although it
causes a wide range of abnormalities, cellular and molecular mechanisms of its action are …

Inflammatory effects of inhaled sulfur mustard in rat lung

R Malaviya, VR Sunil, J Cervelli, DR Anderson… - Toxicology and applied …, 2010 - Elsevier
Inhalation of sulfur mustard (SM), a bifunctional alkylating agent that causes severe lung
damage, is a significant threat to both military and civilian populations. The mechanisms …