LIN28 is an RNA-binding protein that is expressed in many developing tissues. It can block
let-7 (Mirlet7) microRNA processing and help promote pluripotency. We have observed …

lin-28 is a conserved regulator of cell fate succession in animals. In Caenorhabditis elegans,
it is a component of the heterochronic gene pathway that governs larval developmental …

LIN28 is an RNA-binding protein that is best known for its roles in promoting pluripotency via
regulation of the microRNA let-7. However, recent studies have uncovered new roles for …

The evolutionarily conserved gene lin-28 encodes an RNA-binding protein and is an
important regulator of the proper temporal succession of several developmental events in …

Lin28: A MicroRNA Regulator with a Macro Role: Cell Skip to Main Content Advertisement Cell
This journal offers authors two options (open access or subscription) to publish research This …

In the nematode Caenorhabditis elegans, the let-7 microRNA (miRNA) controls the timing of
key developmental events and terminal differentiation in part by directly regulating lin-41. C …

MicroRNAs (miRNAs) are small noncoding RNA molecules that regulate gene expression.
Among these, members of the let-7 miRNA family control many cell-fate determination genes …

Beginning with their discovery in the context of stem cell fate choice in Caenorhabditis
elegans, the microRNA (miRNA) let-7 and the RNA-binding protein Lin28 have been …

One of the most ancient and highly conserved microRNAs (miRNAs), the let-7 family, has
gained notoriety owing to its regulation of stem cell differentiation and essential role in …

Abstract microRNAs shape the identity and function of cells by regulating gene expression. It
is known that brain-specific miR-9 is controlled transcriptionally; however, it is unknown …