Several transport vectors, including nanoparticles, have been reported to be used for the
delivery of therapeutic medicines crossing the impermeable blood-brain barrier (BBB) to …

Abstract Poly (n-butyl-2-cyanoacrylate)(PBCA) nanoparticles have been successfully
applied to deliver small-molecule drugs to the central nervous system (CNS). However, it is …

Currently, traumatic brain injury (TBI) is the leading cause of death or disabilities in young
individuals worldwide. The multi-complexity of its pathogenesis as well as impermeability of …

The nerve growth factor (NGF) is essential for the survival of both peripheral ganglion cells
and central cholinergic neurons in the basal forebrain. The accelerated loss of central …

We induced tissue repair following ischemic stroke in rats by delivering brain-derived
neurotrophic factor (BDNF) directly to the brain. This protein is a potent modulator of …

Purpose Brain-derived neurotrophic factor (BDNF) plays an important role in
neuroprotection and repair, but long-term delivery from polymer systems has been …

Brain-derived neurotrophic factor (BDNF) regulates dendritic branching and dendritic spine
morphology, as well as synaptic plasticity and long-term potentiation. Consequently, BDNF …

Background Low levels of brain-derived neurotrophic factor (BDNF) are linked to delayed
neurological recovery, depression, and cognitive impairment following stroke …

Brain‐derived neurotrophic factor (BDNF) is identified as a potent neuroprotective and
neuroregenerative agent for many neurological diseases. Regrettably, its delivery to the …

Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, is protective
in animal models of neurodegenerative diseases. However, BDNF has a short half-life and …