[HTML][HTML] A composite urine biomarker reflects interstitial inflammation in lupus nephritis kidney biopsies

X Zhang, HN Nagaraja, T Nadasdy, H Song… - Kidney international, 2012 - Elsevier
The initial treatment of lupus nephritis is usually based on a renal biopsy. Subsequent
disease flares, however, are often treated without the benefit of kidney pathology because …

Urinary proteomic profiles distinguish between active and inactive lupus nephritis

K Mosley, FWK Tam, RJ Edwards, J Crozier… - …, 2006 - academic.oup.com
Objectives. Key aims of the treatment of lupus nephritis (LN) are to induce and maintain
remission with minimal side effects. However, assessing ongoing renal inflammatory activity …

Lupus nephritis biomarkers: a critical review

FK Alduraibi, GC Tsokos - International Journal of Molecular Sciences, 2024 - mdpi.com
Lupus nephritis (LN), a major complication in individuals diagnosed with systemic lupus
erythematosus, substantially increases morbidity and mortality. Despite marked …

Clinical evaluation and monitoring of lupus kidney disease

HA Austin - Lupus, 1998 - journals.sagepub.com
Lupus renal involvement encompasses a broad range of clinical and histologic
presentations and poses numerous therapeutic challenges. Accurate clinical assessment …

Biomarkers of lupus nephritis histology and flare: deciphering the relevant amidst the noise

DJ Birmingham, M Merchant, SS Waikar… - Nephrology Dialysis …, 2017 - academic.oup.com
Biomarker development in lupus nephritis (LN) has traditionally relied on comparing the
characteristics of candidate markers to clinical findings in patients and controls from cross …

[HTML][HTML] Urine proteomic signatures of histological class, activity, chronicity, and treatment response in lupus nephritis

A Fava, J Buyon, L Magder, J Hodgin, A Rosenberg… - JCI insight, 2024 - ncbi.nlm.nih.gov
Lupus nephritis (LN) is a pathologically heterogenous autoimmune disease linked to end-
stage kidney disease and mortality. Better therapeutic strategies are needed as only 30 …

Urinary cytokines and mRNA expression as biomarkers of disease activity in lupus nephritis

B Jakiela, J Kosałka, H Plutecka, AS Węgrzyn… - Lupus, 2018 - journals.sagepub.com
Introduction Renal involvement is one of the most serious manifestations of systemic lupus
erythematosus, but non-invasive assessment of inflammatory response in kidneys is …

Identification of urinary metabolites that distinguish membranous lupus nephritis from proliferative lupus nephritis and focal segmental glomerulosclerosis

LE Romick-Rosendale, HI Brunner, MR Bennett… - Arthritis research & …, 2011 - Springer
Introduction Systemic lupus erythematosus (SLE or lupus) is a chronic autoimmune disease,
and kidney involvement with SLE, aka lupus nephritis (LN), is a frequent and severe …

Clinical presentation and monitoring of lupus nephritis

JE Balow - Lupus, 2005 - journals.sagepub.com
The diversity of clinical presentations of lupus nephritis parallel the diversity of pathologic
lesions seen in the kidneys of patients with SLE. Renal manifestations range from …

Lipocalin‐2, TWEAK, and other cytokines as urinary biomarkers for lupus nephritis

N Schwartz, JS Michaelson… - Annals of the New York …, 2007 - Wiley Online Library
Lupus nephritis (LN) is a major cause of morbidity and mortality in systemic lupus
erythematosus (SLE). As the course of LN is often unpredictable, it is important to identify …