Regulation, structure and function of brain aquaporin

Y Masato - Rinsho Shinkeigaku= Clinical Neurology, 2009 - europepmc.org
Discovery of aquaporin water channel proteins has provided insight into the molecular
mechanism of membrane water permeability. In mammalian brain, Aquaporin-4 (AQP4) is …

Aquaporins: multifarious roles in brain

M Amiry-Moghaddam, EH Hoddevik… - …, 2010 - ibroneuroscience.org
Six years have elapsed since the publication of the Neuroscience Special Issue entitled
“Brain Water Homeostasis”(Agre et al., 2004). Several of the chapters in the latter Special …

Upregulation of water channel aquaporin-4 in experimental autoimmune encephalomyeritis

K Miyamoto, N Nagaosa, M Motoyama… - Journal of the …, 2009 - Elsevier
Aquaporin-4 (AQP4) is a water channel protein that plays an important role in water
movement in the central nervous system (CNS). Recently, presence of anti-AQP4 antibody …

Water movements in the brain: role of aquaporins

MJ Tait, S Saadoun, BA Bell… - TRENDS in …, 2008 - cell.com
About 80% of the brain is water. This review discusses the importance of the three brain
water-channel proteins (AQP1, AQP4, AQP9) in brain physiology. AQP1 is expressed in the …

Aquaporin water channels in the nervous system

MC Papadopoulos, AS Verkman - Nature Reviews Neuroscience, 2013 - nature.com
The aquaporins (AQPs) are plasma membrane water-transporting proteins. AQP4 is the
principal member of this protein family in the CNS, where it is expressed in astrocytes and is …

Aquaporin-4: orthogonal array assembly, CNS functions, and role in neuromyelitis optica

AS Verkman, J Ratelade, A Rossi, H Zhang… - Acta Pharmacologica …, 2011 - nature.com
Abstract Aquaporin-4 (AQP4) is a water-selective transporter expressed in astrocytes
throughout the central nervous system, as well as in kidney, lung, stomach and skeletal …

Aquaporin-4 water channel in the brain and its implication for health and disease

S Mader, L Brimberg - Cells, 2019 - mdpi.com
Aquaporin-4 (AQP4) is a water channel expressed on astrocytic endfeet in the brain. The
role of AQP4 has been studied in health and in a range of pathological conditions. Interest in …

Roles of aquaporins in brain disorders

M Yasui - Brain and Nerve= Shinkei Kenkyu no Shinpo, 2015 - europepmc.org
Aquaporin (AQP) is a water channel protein that is expressed in the cell membranes. AQPs
are related to several kinds of human diseases such as cataract. In the mammalian central …

Aquaporins in neurological disorders

L Hirt, M Price, C Benakis… - Clinical and Translational …, 2018 - journals.sagepub.com
Aquaporins (AQPs) are water channel molecules that allow the passage of water through
the lipid bilayers of cell membranes. AQP1, AQP4 and AQP9 are expressed in the central …

Aquaporin-4, homeostasis, and neurologic disease

EE Benarroch - Neurology, 2007 - AAN Enterprises
Aquaporins constitute a family of water channels that regulate the transport of water in
essentially all organs, including the kidney, gastrointestinal tract, secretory glands, inner ear …