Browning of white adipose tissue (WAT) has been shown to reduce obesity and obesity-
related complications, suggesting that factors that promote WAT browning may have …

Browning of white adipose tissue (WAT) is suggested as a promising therapeutic approach
to induce energy expenditure and counteract obesity and its associated complications …

Spinophilin is an F-actin binding and protein phosphatase 1 (PP1) targeting protein that acts
as a scaffold of PP1 to its substrates. Spinophilin knockout (Spino-/-) mice have decreased …

Obesity is a major risk factor for the development of diabetes, insulin resistance,
dyslipidemia, cardiovascular disease and other related metabolic conditions. Obesity …

Aims: The pathogenesis of obesity remains incompletely understood. Drosophila have
conserved neuroendocrine and digestion systems with human and become an excellent …

Overweight and obesity have become a world-wide problem. However, effective intervention
approaches are limited. Brown adipose tissue, which helps maintain body temperature and …

Obesity is associated with metabolic syndrome and other chronic diseases, and is caused
when the energy intake is greater than the energy expenditure. We aimed to determine the …

Background: Two brown-like adipocytes, including classical brown adipocytes from brown
adipose tissues and beige cells from white adipose tissues, regulate thermogenesis. The …

Brown adipose tissue (BAT) plays important roles in regulating energy homeostasis and
combating obesity. Accordingly, increasing the abundance and/or activating BAT would be …

Objective Obesity is associated with low-grade adipose tissue inflammation and locally
elevated levels of several glycoprotein 130 (gp130) cytokines. The conversion of white into …