Human T-cell leukemia virus (HTLV)-infected cell lines derived from adult T-cell leukemia
(ATL) express constitutively the receptor for Interleukin-2 (IL-2-R) and the associated antigen …

Abstract Interleukin-2 (IL-2) is a lymphokine synthesized by some T-cells following
activation. Resting T-cells do not express IL-2 receptors, but receptors are rapidly expressed …

We studied the expression of the interleukin-2 (IL-2) receptor and the proliferative response
to exogenous IL-2 of peripheral blood leukemic cells from patients with adult T cell leukemia …

Late-phase human T-cell lymphotropic virus I-associated adult T-cell leukemia cells express
IL-2 receptors (IL-2R) but no longer produce IL-2. We have reported that the IL-2 …

In early phases of human T-cell lymphotrophic virus I-induced adult T-cell leukemia (ATL),
the malignant cell proliferation is associated with an autocrine process involving coordinate …

Interleukin 2 (IL-2) receptor/Tac antigen is abnormally expressed on cells of patients with
adult T cell leukemia (ATL) caused by infection with human T lymphotropic virus type I …

Human interleukin 2 receptors (IL2R) from various cell sources such as mitogen-activated
normal human T cells, adult T cell leukemia (ATL)-derived cell line cells (MT-1, ATL-6, Hut …

Our knowledge of the mechanism of lymphocyte activation and proliferation by interleukin-2
(IL-2) and interleukin-2 receptor (IL-2-R) has expanded rapidly since the cloning of the …

We established an interleukin 2 (IL-2)-dependent human T cell line, Kit 225, from a patient
with T cell chronic lymphocytic leukemia (T-CLL) with OKT3+,-T4+,-T8-phenotype. Southern …

Adult T-cell leukemia (ATL) cells have been shown to express the receptor for IL-2 by
studies using anti-CD25 monoclonal antibody, but these cells usually show no or only a …