Carvacrol exhibits anti-oxidant and anti-inflammatory effects against 1, 2-dimethyl hydrazine plus dextran sodium sulfate induced inflammation associated …

K Arigesavan, G Sudhandiran - Biochemical and biophysical research …, 2015 - Elsevier
Chronic inflammation is one of the remarkable etiologic factors for various human ailments
including cancer. The well known hypothesis is that persistent inflammation in colon can …

In vitro antiproliferative and antioxidant effects of urolithin A, the colonic metabolite of ellagic acid, on hepatocellular carcinomas HepG2 cells

Y Wang, Z Qiu, B Zhou, C Liu, J Ruan, Q Yan, J Liao… - Toxicology in vitro, 2015 - Elsevier
The intestinal metabolites of ellagic acid (EA), urolithins are known to effectively inhibit
cancer cell proliferation. This study investigates antiproliferative and antioxidant effects of …

Biochanin-A, an isoflavon, showed anti-proliferative and anti-inflammatory activities through the inhibition of iNOS expression, p38-MAPK and ATF-2 phosphorylation …

L Kole, B Giri, SK Manna, B Pal, S Ghosh - European journal of …, 2011 - Elsevier
Biochanin-A, an isoflavone, existing in red clover, cabbage and alfalfa, has an inhibitory and
apoptogenic effect on certain cancer cells. However, the actual mechanism by which this …

In vitro antioxidant and antiproliferative effects of ellagic acid and its colonic metabolite, urolithins, on human bladder cancer T24 cells

Z Qiu, B Zhou, L Jin, H Yu, L Liu, Y Liu, C Qin… - Food and Chemical …, 2013 - Elsevier
Urolithins were the metabolites of ellagic acid by intestinal flora in gastrointestinal tract. In
previous research, it was found that urolithins could mainly inhibit prostate cancer and colon …

Anti-inflammatory effect of 2-methoxy-4-vinylphenol via the suppression of NF-κB and MAPK activation, and acetylation of histone H3

JB Jeong, SC Hong, HJ Jeong, JS Koo - Archives of pharmacal research, 2011 - Springer
Although inflammation acts as host defense mechanism against infection or injury and is
primarily a self limiting process, inadequate resolution of inflammatory responses leads to …

Naringenin (4, 5, 7‐trihydroxyflavanone) suppresses the development of precancerous lesions via controlling hyperproliferation and inflammation in the colon of …

MU Rehman, MU Rahman Mir, A Farooq… - Environmental …, 2018 - Wiley Online Library
Colon cancer is a world‐wide health problem and one of the most dangerous type of cancer,
affecting both men and women. Naringenin (4, 5, 7‐trihydroxyflavanone) is one of the major …

Dose-dependent effect of oregano (Origanum vulgare L.) on lipid peroxidation and antioxidant status in 1,2-dimethylhydrazine-induced rat colon carcinogenesis

T Srihari, M Sengottuvelan… - Journal of Pharmacy and …, 2008 - academic.oup.com
Colon cancer is a major cause of morbidity and mortality in developed and developing
countries. Diet and dietary constituents play a major role in the aetiology of colon cancer. We …

Suppression of inducible nitric oxide synthase and cyclooxygenase‐2 in downregulating nuclear factor‐kappa B pathway by Garcinol

CH Liao, S Sang, YC Liang, CT Ho… - … in cooperation with the …, 2004 - Wiley Online Library
Garcinol is a polyisoprenylated benzophenone derivative of Garcinia indica fruit rind and
other species. Recent studies have demonstrated that garcinol exhibited antioxidative …

Eugenol inhibits cell proliferation via NF-κB suppression in a rat model of gastric carcinogenesis induced by MNNG

P Manikandan, G Vinothini, R Vidya Priyadarsini… - Investigational new …, 2011 - Springer
The modulation of intracellular nuclear factor-kappaB (NF-κB) signaling pathway involved in
the deregulated expression of cell proliferation and cell cycle regulatory molecules is a …

Antitumorigenic and antipromoting activities of ellagic acid, ellagitannins and oligomeric anthocyanin and procyanidin

A Castonguay, H Gali, E Perchellet… - International …, 1997 - spandidos-publications.com
We previously showed that ellagic acid (EA) was inhibiting lung tumorigenesis induced by
the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in …