Ellagic acid facilitates indomethacin-induced gastric ulcer healing via COX-2 up-regulation

A Chatterjee, S Chatterjee, S Das, A Saha… - Acta Biochim …, 2012 - academic.oup.com
The mechanism of indomethacin-induced gastric ulcer healing by ellagic acid (EA) in
experimental mice model is described in our study. Ulcer index (UI) and myeloperoxidase …

Modulation of signalling nuclear factor-κB activation pathway by polyphenols in human intestinal Caco-2 cells

B Romier, J Van De Walle, A During… - British Journal of …, 2008 - cambridge.org
Recent studies support beneficial effects of polyphenols in various chronic inflammatory
diseases, for example, the inflammatory bowel diseases. Inhibition of NF-κB activation by …

Rheosmin, a naturally occurring phenolic compound inhibits LPS-induced iNOS and COX-2 expression in RAW264. 7 cells by blocking NF-κB activation pathway

JB Jeong, HJ Jeong - Food and chemical toxicology, 2010 - Elsevier
Inflammation is part of the host defense mechanism against harmful matters and injury;
however, aberrant inflammation is associated to the development of chronic disease such as …

A novel NF-κB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates inflammatory colonic injury in mice

T Funakoshi, K Yamashita, N Ichikawa… - Journal of Crohn's …, 2012 - academic.oup.com
Background: In inflammatory bowel disease (IBD), gut inflammation is associated with the
activation of nuclear factor kappa B (NF-κB), a key pro-inflammatory transcription factor. Aim …

O-methylated flavonol isorhamnetin prevents acute inflammation through blocking of NF-κB activation

JH Yang, SC Kim, BY Shin, SH Jin, MJ Jo… - Food and Chemical …, 2013 - Elsevier
Here, we isolated isorhamnetin, a natural 3′-O-methylated flavonoid, from water dropwort
(Oenanthe javanica, Umbelliferae) and investigated its ability to protect against acute …

Protective role of luteolin in 1, 2‐dimethylhydrazine induced experimental colon carcinogenesis

V Manju, N Nalini - … and Function: Cellular biochemistry and its …, 2007 - Wiley Online Library
The aim of the present study was to unravel the chemopreventive effect of luteolin on
bacterial enzymes such as β‐glucuronidase and mucinase in a colon carcinogenesis model …

Isoliquiritigenin isolated from the roots of Glycyrrhiza uralensis inhibits LPS-induced iNOS and COX-2 expression via the attenuation of NF-κB in RAW 264.7 …

JY Kim, SJ Park, KJ Yun, YW Cho, HJ Park… - European journal of …, 2008 - Elsevier
In this study, the anti-inflammatory effects of flavonoids isolated from the roots of Glycyrrhiza
uralensis (Leguminosae), namely, isoliquiritin (the glycoside of isoliquirigenin) and …

Anti-inflammatory effect of coumarins isolated from Corydalis heterocarpa in HT-29 human colon carcinoma cells

KH Kang, CS Kong, Y Seo, MM Kim, SK Kim - Food and chemical …, 2009 - Elsevier
We investigated anti-inflammatory effects of two coumarins, columbianetin (A) and
libanoridin (B), isolated from Corydalis heterocarpa in lipopolysaccharide (LPS)-stimulated …

Protective effects of iridoid glycosides on acute colitis via inhibition of the inflammatory response mediated by the STAT3/NF-кB pathway

J Yuan, W Cheng, G Zhang, Q Ma, X Li, B Zhang… - International …, 2020 - Elsevier
Morroniside and loganin are iridoid glycosides extracted from Cornus officinalis, a plant
species widely used in traditional Chinese medicine. However, the anti-inflammatory effects …

Evidence for anti-inflammatory activity of isoliquiritigenin, 18β glycyrrhetinic acid, ursolic acid, and the traditional Chinese medicine plants Glycyrrhiza glabra and …

JX Zhou, M Wink - Medicines, 2019 - mdpi.com
Background: We investigated the effect of root extracts from the traditional Chinese medicine
(TCM) plants Glycyrrhiza glabra L., Paeonia lactiflora Pall., and the leaf extract of Eriobotrya …