Background. We aimed in our study to research the role of new cytokines such as IL‐35, IL‐
22, and IL‐17 that may form a target for novel treatment approaches. Methods. IL‐10, IL‐17 …

Background and objective: CD4+CD25+ regulatory T (Treg) cells play an essential role in
maintaining immune homeostasis. In this study, we investigated whether the induced …

Objectives House dust mite aeroallergens are predominant triggers of frequent asthma
attacks among adults and children. The intensity of asthma and immune reaction …

Background: There is a lack of information about regulatory T cells (Tregs) and inflammatory
phenotypes in patients with asthma. In this study, we aimed to compare the characteristics of …

Allergic diseases such as asthma, rhinitis, and eczema are increasing in prevalence and
affect up to 15% of populations in Westernized countries. The description of Tregs as T cells …

Purpose Allergic rhinitis (AR), is an IgE-mediated inflammation of the nose. Regulatory T
cells (Tregs) and inflammatory cytokines have been shown to play a critical role in allergic …

Abstract Aims Ten-eleven-translocation (Tet) proteins are 5-methylcytosine oxidases and
have profound impact on DNA methylation and genes expression. This study aimed to …

Objectives: To determine the role of regulatory T/type 2 helper cell-mediated immune
imbalance in the pathogenesis of allergic rhinitis and examine the association between …

Recent studies highlight the role of Treg in preventing unnecessary responses to allergens
and maintaining functional immune tolerance in the lung. We investigated the role of Treg …

Background: Allergic rhinitis (AR) is a disease in which T-helper (Th) 2 response is
predominant and its pathogenic mechanism is still poorly understood. Aim: To evaluate the …