Osteoarthritis (OA) is the most prevalent joint disease in older people and is characterized
by the progressive destruction of articular cartilage, synovial inflammation, changes in …

Osteoarthritis (OA), the most common form of degenerative joint disease, is linked to high
morbidity. It is predicted to be the single greatest cause of disability in the general population …

Although osteoarthritis (OA) is the most common musculoskeletal condition that causes
significant health and social problems worldwide, its exact etiology is still unclear. With an …

Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

Objectives As more has become known of the pathophysiology of osteoarthritis (OA),
evidence that inflammation plays a critical role in its development and progression has …

Highlights•Different OA etiologies present a challenge for developing a single targeted
therapy.•Common mechanisms occur in inflammatory, mechanical, and oxidative stress in …

Osteoarthritis, a degenerative joint disease, is the most disabling condition of the Western
world. It affects first and foremost the articular cartilages and leads to a molecular and …

Osteoarthritis (OA) is currently the most widespread musculoskeletal condition and primarily
affects weight-bearing joints such as the knees and hips. Importantly, knee OA remains a …

Great progress continues to be made in our understanding of the multiple facets of
osteoarthritis (OA) biology. Here, we review the major advances in this field and progress …

Osteoarthritis (OA) is a chronic, progressive degenerative whole joint disease that affects the
articular cartilage, subchondral bone, ligaments, capsule, and synovium. While it is still …