The effect of moderate hypoxia on cerebral blood flow (CBF) in man has not been well
described, and little is known about the interaction of changes in arterial PO2 and PCO2 as …

New Findings What is the central question of this study? Do differing magnitudes of
ventilation influence cerebrovascular CO2 reactivity and the cerebral blood flow response to …

This study examined the dynamics of the cerebral blood flow response to hypoxia and
hypercapnia in humans. Middle cerebral artery blood flow (MCAF) was assessed …

Both hypoxia and carbon dioxide increase cerebral blood flow (CBF), and their effective
interaction is currently thought to be additive. Our objective was to test this hypothesis. Eight …

This study examined the effect of high, normal, and uncontrolled end-tidal Pco2 (PetCO2) on
the ventilatory, peak cerebral blood flow velocity (V̄ p), and mean arterial blood pressure …

Cerebral blood flow (CBF) is highly regulated by changes in arterial Pco2 and arterial Po2.
Evidence from animal studies indicates that various vasoactive factors, including release of …

To assess the effect of brain blood flow on hypoxic ventilatory response, we measured
arterial and internal jugular venous blood gases and ventilation simultaneously and …

We designed the present study to see whether, during acute moderate isocapnic
hypoxemia, changes in cerebral vascular resistance (CVR) and brain extracellular fluid …

Alterations in arterial oxygen and carbon dioxide influence cerebrovascular resistance and
therefore cerebral blood flow (CBF), but the magnitude of these CBF responses have not …

We examined changes in the blood flow velocity of brain stem artery (BSA) and middle
cerebral artery (MCA) in response to hypercapnic, normocapnic and hypocapnic …