mRNA export involves association of mRNAs with nucleoplasmic proteins, delivery to the
nuclear pore complex, translocation to the cytoplasm, and reimport of recycling components …

Cellular mRNAs are produced in the nucleus and must be exported to the cytoplasm to allow
for their translation into proteins. Recruitment of export factors to nascent mRNA starts …

Three independent pathways of nuclear import have so far been identified in yeast, each
mediated by cognate nuclear transport factors, or karyopherins. Here we have characterized …

Fully processed mRNAs are exported to the cytoplasm where they direct protein synthesis. A
general feature of mRNA export is that it is an active, receptor-mediated process. The mRNA …

mRNAs are transported from the nucleus to the cytoplasm by a machinery conserved from
yeast to humans. Previous studies showed that mRNA export factors are loaded on nascent …

Background CRM1, an evolutionarily conserved protein, was shown to be a receptor for
leucine‐rich nuclear export signal (NES)‐dependent protein transport. In lower eukaryotes …

Export of mRNA from the nucleus to the cytoplasm is a critical process for all eukaryotic gene
expression. As mRNA is synthesized, it is packaged with a myriad of RNA‐binding proteins …

The Ran protein regulates nucleocytoplasmic transport mediated by the karyopherin family
of nuclear transport factors. Ran is converted to the active, GTP bound form in the nucleus …

Following transcription and processing, eukaryotic mRNAs are exported from the nucleus to
the cytoplasm for translation. Here we present evidence that mRNAs are targeted for nuclear …

Export of mRNA through nuclear pore complexes (NPC) is preceded by multiple and well
coordinated processing steps, resulting in the formation of an export competent …