BACKGROUND: There is a paucity of data available regarding the dosing of antimicrobials
in obesity. However, data are available demonstrating that vancomycin should be dosed on …

Study Objective To compare the effects of empiric vancomycin dosing regimens on
attainment of optimal target trough concentrations in obese (body mass index [BMI] 30–40 …

Objectives and methods: Vancomycin hydrochloride dosing requirements in morbidly obese
patients with normal renal function were computed to determine the dose of vancomycin …

Vancomycin was the first glycopeptide antibiotic introduced into clinical practice. Despite the
numerous benefits of vancomycin, clinicians have struggled to dose vancomycin …

Background: Data are lacking to guide antimicrobial dosing for overweight children. The
authors hypothesized that obese children would have increased vancomycin serum trough …

Purpose An original and a revised vancomycin dosing protocol for obese patients were
compared with respect to attainment of target serum trough vancomycin concentrations and …

Background Obese patients display differences in vancomycin drug disposition, which may
complicate attainment of appropriate serum vancomycin concentrations (SVCs). This study …

Background Optimal dosing of vancomycin in morbidly obese patients (> 100 kg and at least
140% of their ideal body weight) has not been determined. Conventional dosing strategies …

Objective: To review the literature regarding vancomycin pharmacokinetics in obese patients
and strategies used to improve dosing in this population. Data Sources: PubMed, EMBASE …

Study Objective To estimate vancomycin pharmacokinetic parameters and dosing
requirements in a cohort of extremely obese patients. Design Prospective pharmacokinetic …