NF-κB inhibitory and cytotoxic activities of hexacyclic triterpene acid constituents from Glechoma longituba

XL Ouyang, F Qin, RZ Huang, D Liang, CG Wang… - Phytomedicine, 2019 - Elsevier
Abstract Background Non-Small-Cell Lung Cancer (NSCLC) is the most-frequent cause of
cancer death, and novel chemotherapeutic drugs for treating NSCLC are urgently needed …

Anti-inflammatory effects of sulfuretin from Rhus verniciflua Stokes via the induction of heme oxygenase-1 expression in murine macrophages

DS Lee, GS Jeong, B Li, H Park, YC Kim - International …, 2010 - Elsevier
Rhus verniciflua Stokes (Anacardiaceae) has traditionally been used as an ingredient in
East Asian medicines used to treat oxidative damage and cancer. Sulfuretin is one of the …

Esculentoside B inhibits inflammatory response through JNK and downstream NF-κB signaling pathway in LPS-triggered murine macrophage RAW 264.7 cells

F Abekura, J Park, CH Kwak, SH Ha, SH Cho… - International …, 2019 - Elsevier
Natural compound esculentoside B (EsB),(2S, 4aR, 6aR, 6aS, 6bR, 8aR, 9R, 10R, 11S,
12aR, 14bS)-11-hydroxy-9-(hydroxymethyl)-2 methoxycarbonyl-2, 6a, 6b, 9, 12a …

The Protective Effect of Artesunate on LPS‐Induced Acute Respiratory Distress Syndrome through Inhibiting NLRP3 Inflammasome Signaling

Y Cui, W Weng, Q Ding, Q Su… - … and Alternative Medicine, 2022 - Wiley Online Library
Background. Artesunate (AS) is a derivative of artemisinin that can exert anti‐inflammatory
effects. This study aims to explore the effect of AS on lipopolysaccharide (LPS)‐induced …

LFG-500, a novel synthetic flavonoid, suppresses epithelial–mesenchymal transition in human lung adenocarcinoma cells by inhibiting NLRP3 in inflammatory …

D Yang, X Cao, F Wang, H Jiang, D Feng, H Guo, L Du… - Cancer letters, 2017 - Elsevier
Increasing evidence indicates that inflammatory microenvironment facilitates tumor
metastasis. Here, we found that LFG-500, a novel synthetic flavonoid, significantly inhibited …

[HTML][HTML] Eriodictyol inhibits the motility, angiogenesis and tumor growth of hepatocellular carcinoma via NLRP3 inflammasome inactivation

W Huang, C Wang, H Zhang - Heliyon, 2024 - cell.com
NLRP3 involves in the development of hepatocellular carcinoma (HCC). Eriodictyol has
shown its inhibitory effect on HCC cell proliferation. However, the underlying mechanism of …

[HTML][HTML] The Essential Oil of Artemisia argyi H.Lév. and Vaniot Attenuates NLRP3 Inflammasome Activation in THP-1 Cells

P Chen, Q Bai, Y Wu, Q Zeng, X Song, Y Guo… - Frontiers in …, 2021 - frontiersin.org
Artemisia argyi H. Lév. and Vaniot is a traditional medical herb that has been used for a long
time in China and other Asian counties. Essential oil is the main active fraction of Artemisia …

JFNE-A isolated from Jing-Fang n-butanol extract attenuates lipopolysaccharide-induced acute lung injury by inhibiting oxidative stress and the NF-κB signaling …

Z Rao, J Zeng, X Li, L Peng, B Wang, F Luan, N Zeng - Phytomedicine, 2022 - Elsevier
Abstract Background Jing-Fang powder consists of Jingjie (Nepeta tenuifolia
Benth,(Lamiaceae)). and Fangfeng (Saposhnikovia divaricata (Turcz.) Schischk,(Apiaceae)) …

[HTML][HTML] Isovitexin exerts anti-inflammatory and anti-oxidant activities on lipopolysaccharide-induced acute lung injury by inhibiting MAPK and NF-κB and activating …

H Lv, Z Yu, Y Zheng, L Wang, X Qin… - International journal of …, 2016 - ncbi.nlm.nih.gov
Oxidative damage and inflammation are closely associated with the pathogenesis of acute
lung injury (ALI). Thus, we explored the protective effect of isovitexin (IV), a …

[HTML][HTML] Anticancer mechanism of breviscapine in non-small cell lung cancer A549 cells acts via ROS-mediated upregulation of IGFBP4

W Wei, L Wang, L Xu, J Zeng - Journal of thoracic disease, 2021 - ncbi.nlm.nih.gov
Background The overall 5-year survival rate of non-small cell lung cancer (NSCLC) is less
than 15% because of multiple drug resistance to chemotherapy and the limitations of early …