Aloperine alleviates lipopolysaccharide-induced acute lung injury by inhibiting NLRP3 inflammasome activation

J Zeng, J Liu, JH Huang, SP Fu, XY Wang, C Xi… - International …, 2023 - Elsevier
Rationale Excessive activation of the NLRP3 inflammasome is involved in the pathological
progression of acute lung injury (ALI). Aloperine (Alo) has anti-inflammatory effects in many …

Chalcones display anti-nlrp3 inflammasome activity in macrophages through inhibition of both priming and activation steps—structure-activity-relationship and …

WJ Leu, JC Chu, JL Hsu, CM Du, YH Jiang, LC Hsu… - Molecules, 2020 - mdpi.com
Chalcones are responsible for biological activity throughout fruits, vegetables, and medicinal
plants in preventing and treating a variety of inflammation-related diseases. However, their …

Anti-inflammatory activity of Eupatorium perfoliatum L. extracts, eupafolin, and dimeric guaianolide via iNOS inhibitory activity and modulation of inflammation-related …

M Maas, AM Deters, A Hensel - Journal of ethnopharmacology, 2011 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Eupatorium perfoliatum L. has been used
traditionally for the treatment of fever, malaria and inflammation-associated diseases …

Sinensetin Attenuated Macrophagic NLRP3 Inflammasomes Formation via SIRT1-NRF2 Signaling

L Lin, K Deng, Z Gong, H Fan, D Zhang, G Lu - ACS omega, 2023 - ACS Publications
Macrophage-mediated inflammation plays essential roles in multiple-organ injury.
Sinensetin (SNS) at least exhibits anti-inflammation, antioxidant, and antitumor properties …

Bioactivity-Guided Extract Optimization of Osmanthus fragrans var. aurantiacus Leaves and Anti-Inflammatory Activities of Phillyrin

HY Song, DE Jeong, M Lee - Plants, 2021 - mdpi.com
The aim of this study was to identify the optimal extraction conditions for leaves of
Osmanthus fragrans var. aurantiacus. Inhibitory effects of various extracts on NO production …

Anemoside B4 protects against acute lung injury by attenuating inflammation through blocking NLRP3 inflammasome activation and TLR4 dimerization

R Yuan, J He, L Huang, LJ Du, H Gao… - Journal of …, 2020 - Wiley Online Library
Acute lung injury (ALI) is an acute inflammatory process in the lung parenchyma. Anemoside
B4 (B4) was isolated from Pulsatilla, a plant‐based drug against inflammation and …

Eupatorium lindleyanum DC. sesquiterpenes fraction attenuates lipopolysaccharide-induced acute lung injury in mice

C Chu, H Ren, N Xu, L Xia, D Chen, J Zhang - Journal of …, 2016 - Elsevier
Ethnopharmacological relevance Eupatorium lindleyanum DC. is widely used for its
efficiency in treating cough, tracheitis and tonsillitis. Acute lung injury (ALI) induced by …

[HTML][HTML] Effective-component compatibility of Bufei Yishen formula alleviates chronic obstructive pulmonary disease inflammation by regulating GSK3β-mediated …

Y Qin, J Zhai, J Yang, H Li, Y Tian, X Liu… - Biomedicine & …, 2023 - Elsevier
Glycogen synthase kinase 3β (GSK3β) has been associated with sensing many different
stimuli to trigger the NLRP3 inflammasome, which plays a crucial role in promoting the …

[HTML][HTML] Ajania purpurea extract attenuates LPS-induced inflammation in RAW264. 7 cells and peritonitis mice

X Wang, Z Dongzhi, Y Li, M Xie, X Li… - Biological and …, 2022 - jstage.jst.go.jp
Macrophages have important roles in the progression of inflammation. Ajania purpurea
Shih. is a member of the Ajania Poljakor family that grows in Tibet (China). Extracts from …

Effusanin E suppresses nasopharyngeal carcinoma cell growth by inhibiting NF-κB and COX-2 signaling

M Zhuang, M Zhao, H Qiu, D Shi, J Wang, Y Tian, L Lin… - PloS one, 2014 - journals.plos.org
Rabdosia serra is well known for its antibacterial, anti-inflammatory and antitumor activities,
but no information has been available for the active compounds derived from this plant in …