Hepatic injury induced by ischemia and reperfusion is an important clinical problem after
liver resection or transplantation. Neutrophils are known to mediate the organ injury, but the …

Hepatic injury induced by ischemia and reperfusion is an important clinical problem after
liver resection or transplantation. Neutrophils are known to mediate the organ injury, but the …

Background. Hepatic ischemia/reperfusion injury during both hepatic resection and
transplantation may lead to local and systemic organ dysfunction. Proinflammatory …

Generation and functional significance of CXC chemokines for neutrophil-induced liver
injury during endotoxemia. Am J Physiol Gastrointest Liver Physiol 288: G880–G886, 2005 …

Tissue accumulation of leukocytes constitutes a rate-limiting step in endotoxin-induced
tissue injury. Chemokines have the capacity to regulate leukocyte trafficking. However, the …

Background. Cytokine production is a critical component of ischemia/reperfusion (IR) injury.
In the liver, Kupffer cells produce cytokines and chemokines (ie, cytokines with …

The CXC chemokines have well-documented neutrophil chemotactic, angiogenic, and
mitogenic properties. The current investigations evaluate the effects of interleukin-8 (IL-8) …

CXC chemokines and their receptor, CXC chemokine receptor‐2 (CXCR2), are important
components of the hepatic inflammatory response to ischemia/reperfusion (I/R). However …

Abstract Macrophage inflammatory protein (MIP)-2 is one of the CXC chemokines and is
also known as chemokine CXC ligand (CXCL2). MIP-2 affects neutrophil recruitment and …

Background/Aims: Macrophage inflammatory protein-2 (MIP-2), one of the CXC chemokines,
is involved in the recruitment of neutrophils in several tissue injuries. In this study, we …