In sickle cell disease, various disturbances commonly affect the bones and joints. Vaso-
occlusive events in blood vessels that traverse the bones cause acute and chronic morbidity …

Sickle cell disease (SCD) is a group of inherited disorders caused by a mutation of the
hemoglobin gene, resulting in the formation of abnormal, sickle-shaped red blood cells. It is …

The bony skeleton of the patient with sickle cell disease is a frequent target of the
consequences of sickling. Bone marrow necrosis, bone infarcts, osteomyelitis, and aseptic …

Sickle cell disease (SCD) is an autosomal recessive disorder that results in hemolytic
anemia related to abnormal hemoglobin and erythrocyte levels. SCD is characterized by …

Sickle cell disease involves many organs but musculo-skeletal problems present most often
with bone pain, the most common reason for admission to hospital. Two separate …

Sickle cell disease (SCD) is an inherited disorder of abnormal haemoglobin commonly
encountered in the West African sub-region. It has varied osteoarticular and non-osseous …

The phenotypic expression of sickle cell disease (SCD) varies greatly among patients and
longitudinally in the same patient. The phenotype influences all aspects of the life of affected …

Sickle-cell disease (SCD) is a worldwide distributed hemoglobinopathy, characterized by
hemolytic anemia associated with vaso-occlusive events. These result in acute and chronic …

Sickle cell anaemia is an autosomal recessive genetic condition producing abnormal
haemoglobin HbS molecules that result in stiff and sticky red blood cells leading to …

The osteoarticular involvement in sickle cell disease has been poorly studied and it is mainly
characterized by osteonecrosis, osteomyelitis and arthritis. The most frequent complications …