Companion diagnostics: the key to personalized medicine

JT Jørgensen - Expert review of molecular diagnostics, 2015 - Taylor & Francis
This special focus issue of Expert Review of Molecular Diagnostics on in vitro companion
diagnostics aims to provide the reader with up-to-date knowledge on this fast-evolving area …

The biomarker is not the end

M Nohaile - Drug discovery today, 2011 - Elsevier
As drug discovery and translational scientists think about using stratification with biomarkers
to improve the chances of getting medicines to patients, several areas of expertise need to …

[PDF][PDF] Biomarkers in drug development and patient care

M Svinte, B Robson, M Hehenberger - Burrill Personalized Medicine …, 2007 - academia.edu
Patients expect medical treatments that work and are safe and “right” for them as individuals.
Biomarkers can help bio-pharmaceutical and diagnostics companies to focus more on …

[HTML][HTML] Molecular Diagnostics: at the nexus of individualized medicine, health care delivery, and public policy

SA Waldman, A Terzic - Clinical and translational science, 2009 - ncbi.nlm.nih.gov
Advances in decoding integrated biological processes; the surge in enabling technologies
including the highthroughput platforms of genomics, proteomics, and metabolomics; and the …

Genome-wide screening for drug discovery and companion diagnostics

AD Roses - Expert Opinion on Drug Discovery, 2007 - Taylor & Francis
Changes in technology can often affect society and models of industry. The broad
expectations for 'genomics' that were highly publicized during the previous decade have not …

Next-generation companion diagnostics: promises, challenges, and solutions

JD Khoury, DVT Catenacci - Archives of Pathology and …, 2015 - meridian.allenpress.com
Companion diagnostics are in vitro clinical laboratory assays designed to predict the efficacy
of a targeted cancer therapy through assessment of 1 or more biomarkers whose status in a …

Clinical perspectives on targeting therapies for personalized medicine

DRJ Singer, ZM Zaïr - Advances in Protein Chemistry and Structural Biology, 2016 - Elsevier
Expected benefits from new technology include more efficient patient selection for clinical
trials, more cost-effective treatment pathways for patients and health services and a more …

Impact of biomarkers on personalized medicine

P Carrigan, T Krahn - New Approaches to Drug Discovery, 2016 - Springer
The field of personalized medicine that involves the use of measuring biomarkers in clinical
samples is an area of high interest and one that has tremendous impact on drug …

Evaluating Novel Biomarkers for Personalized Medicine

T Drugan, D Leucuța - Diagnostics, 2024 - mdpi.com
Personalized medicine, sometimes referred to as precision medicine, is a paradigm shift in
healthcare. This model is based on the concept of customizing prevention and treatment …

Genomic biomarkers for patient selection and stratification: the cancer paradigm

SA Moschos - Bioanalysis, 2012 - Taylor & Francis
The revolution in disease diagnosis and treatment promised on the completion of the human
genome project over a decade ago has materialized in the form of unified drug and …