Our understanding of alcohol use disorder (AUD), particularly alcohol's effects on the
nervous system, has unquestionably benefited from the use of model systems such as …

Alcohol is a widely used and abused substance with numerous negative consequences for
human health and safety. Historically, alcohol's widespread, non-specific neurobiological …

Alcohol Use Disorder (AUD) is a debilitating disorder that manifests as problematic patterns
of alcohol use. At the core of AUD's behavioral manifestations are the profound structural …

Alcohol abuse is a pervasive problem known to be influenced by genetic factors, yet our
understanding of the mechanisms underlying alcohol addiction is far from complete …

Alcohol use disorders (AUDs) are very common worldwide and negatively affect both
individuals and societies. To understand how normal behavior turns into uncontrollable use …

Our understanding of the networks of genes and protein functions involved in Alcohol Use
Disorder (AUD) remains incomplete, as do the mechanisms by which these networks lead to …

In free nature, animals rarely become alcoholics. Only when humans interfere do they
develop some aspects of dependence. In humans, it is thought that 40–60% of the risk to …

Background Despite the profound clinical significance and strong heritability of alcohol use
disorder (AUD), we do not yet have a comprehensive understanding of the naturally …

Animal models have been widely used to gain insight into the mechanisms underlying the
acute and long-term effects of alcohol exposure. The fruit fly Drosophila melanogaster …

Alcohol addiction is a complex, unique human disease. Breaking addiction down into
contributing endophenotypes enables its study in a variety of model systems. The …