DNA methylation is a dynamic, reversible and heritable epigenetic modification pattern that
mainly occurs in mammalian primordial germ cells and early embryonic development. DNA …

DNA methylation is of paramount importance for mammalian embryonic development. DNA
methylation has numerous functions: it is implicated in the repression of transposons and …

Methylation of DNA is an essential epigenetic control mechanism in mammals. During
embryonic development, cells are directed toward their future lineages, and DNA …

DNA methylation and demethylation are crucial for modulating gene expression and
regulating cell differentiation. Functions and mechanisms of DNA methylation/demethylation …

DNA methylation in mammals is a key epigenetic modification essential to normal genome
regulation and development. DNA methylation patterns are established during early …

DNA methylation occurs on cytosines, is catalyzed by DNA methyltransferases (DNMTs),
and is present at high levels in all vertebrates. DNA methylation plays essential roles in …

DNA methylation is a major epigenetic regulatory mechanism for gene expression and cell
differentiation. Until recently, it was still unclear how unmethylated regions in mammalian …

Cytosine methylation in mammals is an epigenetic modification required for viability of the
developing embryo. It has been suggested that DNA methylation plays important roles in X …

DNA methylation is dynamically reprogrammed at two developmental periods, in primordial
germ cells and pre-implantation embryos, via distinct phases of DNA demethylation and de …

DNA methylation is one of many epigenetic mechanisms that regulate gene expression in
the human body. From the view of epigenetics, there are two phases of development, one for …