These NCCN Guidelines Insights focus on recent updates to the 2015 NCCN Guidelines for
Non–Small Cell Lung Cancer (NSCLC). Appropriate targeted therapy is very effective in …

Background The goals of this multinational retrospective study were to describe treatment
patterns and survival outcomes by receipt of molecular testing and molecular status of …

Background National guidelines have advocated broad molecular profiling as a part of the
standard diagnostic evaluation for advanced non–small cell lung cancer (NSCLC), with the …

Purpose To establish a baseline for care and overall survival (OS) based upon
contemporary first-line treatments prescribed in the era before the introduction of immune …

Precision oncology comprises the set of strategies that aim to design the best cancer
treatment based on tumor biology. A recognized subset of patients with non‐small cell lung …

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Non–Small Cell
Lung Cancer (NSCLC) provide recommended management for patients with NSCLC …

Non-small cell lung cancers (NSCLCs) are heterogeneous cancers. In 2004, the
identification of epidermal growth factor receptor (EGFR) somatic mutations provided the first …

Substantial advances have been made in understanding critical molecular and cellular
mechanisms driving tumor initiation, maintenance, and progression in non–small-cell lung …

Background Testing for EGFR mutations and ALK rearrangement has become standard in
managing advanced nonsmall-cell lung cancer (NSCLC). However, many institutions in …

Non–small-cell lung cancer (NSCLC) has recently been associated with interesting
molecular characteristics that have important implications in carcinogenesis and response to …