Airway hyperresponsiveness (AHR) is characterized by excessive bronchoconstriction in
response to nonspecific stimuli, thereby leading to airway stenosis and increased airway …

Background Air pollutants are important factors that contribute to the development and
exacerbation of asthma, but experimental evidence still needs to be collected and the …

Oxidative stress is defined as the imbalance between reactive oxygen species (ROS)
production and the endogenous antioxidant defense system, leading to cellular damage …

Exposure to fine particulate matter (PM 2.5) has been associated with lung inflammation and
airway hyperresponsiveness (AHR). Transient receptor potential (TRP) vanilloid 1 (TRPV1) …

Background Exposure to airborne particulate matter (PM), a major component of air
pollution, has been associated with increases in both exacerbations of and hospitalizations …

Epidemiologic studies have suggested that exposure to airborne particulate matter (PM) can
exacerbate allergic airway responses; however, the mechanism (s) are not well understood …

We investigated the mechanism responsible for the oxidative stress and pro-inflammatory
response triggered by PM 2.5 collected from Nanjing of China. Two human bronchial …

The present study aimed to examine the effects of 2.5 µm particulate matter (PM2. 5) on
airway inflammation and to investigate the possible underlying mechanism. Specifically, the …

Outdoor air pollution is a major environmental health problem throughout the world. In
particular, exposure to particulate matter (PM) has been associated with the development …

Background Several epidemiological and laboratory studies have evidenced the fact that
atmospheric particulate matter (PM) increases the risk of respiratory morbidity. It is well …