Vascular inflammation in hypertension and diabetes: molecular mechanisms and therapeutic interventions

C Savoia, EL Schiffrin - Clinical science, 2007 - portlandpress.com
More than 80% of patients with type 2 diabetes mellitus develop hypertension, and approx.
20% of patients with hypertension develop diabetes. This combination of cardiovascular risk …

Vascular inflammation: a role in vascular disease in hypertension?

A Virdis, EL Schiffrin - Current opinion in nephrology and …, 2003 - journals.lww.com
Inflammatory mechanisms are important participants in the pathophysiology of hypertension
and cardiovascular disease. The identification of useful markers of inflammation, of new …

Diabetes is a proinflammatory state: a translational perspective

S Devaraj, MR Dasu, I Jialal - Expert review of endocrinology & …, 2010 - Taylor & Francis
The diabetic state confers an increased propensity to accelerated atherogenesis.
Inflammation is pivotal in atherosclerosis; in addition to the established risk factors …

Roles of inflammation, oxidative stress, and vascular dysfunction in hypertension

QN Dinh, GR Drummond, CG Sobey… - BioMed research …, 2014 - Wiley Online Library
Hypertension is a complex condition and is the most common cardiovascular risk factor,
contributing to widespread morbidity and mortality. Approximately 90% of hypertension …

Is hypertension an inflammatory disease?

JJ Li, CH Fang, RT Hui - Medical hypotheses, 2005 - Elsevier
Hypertension has been recognized as a multi-factorial trait resulting from the effect of a
combination of environmental and genetic factors, including excess dietary salt or alcohol …

[HTML][HTML] Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms

JR Petrie, TJ Guzik, RM Touyz - Canadian Journal of Cardiology, 2018 - Elsevier
Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as
frequent in patients with diabetes compared with those who do not have diabetes. Moreover …

Inflammation may be a bridge connecting hypertension and atherosclerosis

JJ Li, JL Chen - Medical hypotheses, 2005 - Elsevier
Pathogenesis of the atherosclerotic process is deemed as multi-factorial, and characterized
by chronic inflammatory response. Although hypertension is known to be one of the most …

Role of the renin–angiotensin system in vascular inflammation

C Marchesi, P Paradis, EL Schiffrin - Trends in pharmacological sciences, 2008 - cell.com
Angiotensin (Ang) II, the main effector of the renin–angiotensin system (RAS), is one of the
major mediators of vascular remodeling in hypertension. Besides being a potent vasoactive …

Molecular and cellular mechanisms in vascular injury in hypertension: role of angiotensin II–editorial review

RM Touyz - Current opinion in nephrology and hypertension, 2005 - journals.lww.com
Inflammation, oxidative stress and hypertension are closely interrelated. Here we discuss
the (patho) physiology of vascular inflammation in hypertension, focusing specifically on the …

Inflammation in hypertension

C Savoia, EL Schiffrin - Current opinion in nephrology and …, 2006 - journals.lww.com
Inflammatory processes are important participants in the pathophysiology of hypertension
and cardiovascular disease. The identification of the mechanisms leading to the activation of …