Electrospun vascular grafts with improved compliance matching to native vessels

RM Nezarati, MB Eifert, DK Dempsey… - … Research Part B …, 2015 - Wiley Online Library
Coronary artery bypass grafting is one of the most commonly performed major surgeries in
the United States. Autologous vessels such as the saphenous vein are the current gold …

Electrospun tissue-engineered arterial graft thickness affects long-term composition and mechanics

YL Wu, JM Szafron, KM Blum, JC Zbinden… - … Engineering Part A, 2021 - liebertpub.com
Wall stress is often lower in tissue-engineered constructs than in comparable native tissues
due to the use of stiff polymeric materials having thicker walls. In this work, we sought to …

Highly compliant biomimetic scaffolds for small diameter tissue-engineered vascular grafts (TEVGs) produced via melt electrowriting (MEW)

A Weekes, G Wehr, N Pinto, J Jenkins, Z Li… - …, 2023 - iopscience.iop.org
Biofabrication approaches toward the development of tissue-engineered vascular grafts
(TEVGs) have been widely investigated. However, successful translation has been limited to …

Impact of elastin incorporation into electrochemically aligned collagen fibers on mechanical properties and smooth muscle cell phenotype

TU Nguyen, CA Bashur, V Kishore - Biomedical Materials, 2016 - iopscience.iop.org
Application of tissue-engineered vascular grafts (TEVGs) for the replacement of small-
diameter arteries is limited due to thrombosis and intimal hyperplasia. Previous studies have …

Construction and characterization of an electrospun tubular scaffold for small-diameter tissue-engineered vascular grafts: A scaffold membrane approach

JJ Hu, WC Chao, PY Lee, CH Huang - Journal of the mechanical behavior …, 2012 - Elsevier
Based on a postulate that the microstructure of a scaffold can influence that of the resulting
tissue and hence its mechanical behavior, we fabricated a small-diameter tubular scaffold …

Novel electrospun polyurethane/gelatin composite meshes for vascular grafts

N Detta, C Errico, D Dinucci, D Puppi… - Journal of Materials …, 2010 - Springer
Novel polymeric micro-nanostructure meshes as blood vessels substitute have been
developed and investigated as a potential solution to the lack of functional synthetic small …

Elastin and collagen enhances electrospun aligned polyurethane as scaffolds for vascular graft

CS Wong, X Liu, Z Xu, T Lin, X Wang - Journal of Materials Science …, 2013 - Springer
Mismatch in mechanical properties between synthetic vascular graft and arteries contribute
to graft failure. The viscoelastic properties of arteries are conferred by elastin and collagen …

Fabrication of burst pressure competent vascular grafts via electrospinning: effects of microstructure

S Drilling, J Gaumer, J Lannutti - … Part A: An Official Journal of …, 2009 - Wiley Online Library
In this work, electrospun tubes of interest for vascular tissue engineering were fabricated
and evaluated for burst pressure and suture retention strength (SRS) in the same context as …

In vivo stability of polyurethane-based electrospun vascular grafts in terms of chemistry and mechanics

AA Gostev, IK Shundrina, VI Pastukhov, AV Shutov… - Polymers, 2020 - mdpi.com
The biostability of the polyurethanes Tecoflex EG-80A and Pellethane 2363-80A, used as
basic polymers of the vascular grafts (VGs) produced by electrospinning, as well as the …

Electrospun biphasic tubular scaffold with enhanced mechanical properties for vascular tissue engineering

A Abdal-Hay, M Bartnikowski, S Hamlet… - Materials Science and …, 2018 - Elsevier
Polymer scaffolds produced through an electrospinning process are frequently explored as
tissue substitutes for regenerative medicine. Despite offering desirable surface area to …