Cardiovascular disease (CVD) accounts for a significant mortality rate worldwide.
Autologous vessels, such as the saphenous vein and the internal mammary artery, are …

Despite the tremendous advances in the past few decades, the clinical problems associated
with low mechanical strength, thrombosis, and inadequate endothelialization still have not …

Small-diameter synthetic vascular grafts have high failure rate due to primarily surface
thrombogenicity, and effective surface chemical modification is critical to maintain the …

Small-diameter vascular grafts (SDVGs)(D< 6 mm) are increasingly needed in clinical
settings for cardiovascular disease, including coronary artery and peripheral vascular …

Aims: To date, there is still a great need for a fully viable small diameter (< 6mm) polymeric
vascular graft. Currently in such low flow locations, non-elastic expanded …

Tissue engineering is an alternative approach for the preparation of small-diameter (< 6mm)
vascular grafts due to the potential to control thrombosis, anastomotic cellular hyperplasia …

Autologous and synthetic vessel grafts have been used as a vascular substitute for
cardiovascular bypass procedures. However, these materials are limited by the availability …

We report biodegradable thermoplastic polyurethanes for soft tissue engineering
applications, where frequently used carboxylic acid ester degradation motifs were …

Herein we combine cell sheet technology and electrospun scaffolding to rapidly generate
circumferentially aligned tubular constructs of human aortic smooth muscles cells with …

Although engineered blood vessels have seen important advances during recent years,
proper mechanical strength and vasoactivity remain unsolved problems. In the current study …