Although not directly cytopathic, hepatitis B and C viruses (HBV and HCV) are responsible
for millions of deaths per year, and the aging patient population presents a severe public …

The human interferon (IFN) response is a key innate immune mechanism to fight virus
infection. IFNs are host‐encoded secreted proteins, which induce IFN‐stimulated genes …

The ability of a host to curb a viral infection is heavily reliant on the effectiveness of an initial
antiviral innate immune response, resulting in the upregulation of interferon (IFN) and …

Chronic hepatitis C virus (HCV) infection is a global public health problem. HCV infection is
treated with type I interferon (IFN), a natural product that is produced by cells during virus …

Type-III interferons (IFN-λ, IFNL) are the most recently described family of IFNs. This family of
innate cytokines are increasingly being ascribed pivotal roles in host–pathogen interactions …

Infection with hepatitis C virus (HCV), a major viral cause of chronic liver disease, frequently
progresses to steatosis and cirrhosis, which can lead to hepatocellular carcinoma. HCV …

The innate immune response is triggered by a variety of pathogens, including viruses, and
requires rapid induction of type I interferons (IFN), such as IFNβ and IFNα. IFN induction …

Hepatitis C virus (HCV) infections become chronic in the majority of infected individuals, and
chronic hepatitis C (CHC) can lead to cirrhosis and hepatocellular carcinoma. The innate …

Hepatitis B virus (HBV) and hepatitis C virus (HCV) cause a large proportion of acute and
chronic liver disease worldwide. Over the past decades many immunological studies …

Hepatitis C virus is a global health concern, estimated to infect 2–3% of the world's
population. Inter-individual differences in the course of infection and response to therapy …