Specific Vesicular Acetylcholine Transporter Promoters Lie within the First Intron of the Rat Choline Acetyltransferase Gene (∗)

R Cervini, L Houhou, S Béjanin, J Mallet… - Journal of Biological …, 1995 - ASBMB
The sequence encoding the vesicular acetylcholine transporter (VAChT) has recently been
localized within the first intron of the choline acetyltransferase (ChAT) gene in various …

Molecular characterization of the mouse vesicular acetylcholine transporter gene

JM Naciff, H Misawa, JR Dedman - Neuroreport, 1997 - journals.lww.com
THE organization of the mouse choline acetyltransferase (ChAT) gene has been previously
analyzed. Here we show that the first intron of the mouse ChAT gene contains an …

A unique gene organization for two cholinergic markers, choline acetyltransferase and a putative vesicular transporter of acetylcholine.

S Bejanin, R Cervini, J Mallet, S Berrard - Journal of Biological Chemistry, 1994 - ASBMB
Choline acetyltransferase (ChAT) is the biosynthetic enzyme of acetylcholine. In mammalian
tissues, it is encoded by multiple mRNAs with different 5 '-ends. This diversity results from …

Expression of the putative vesicular acetylcholine transporter in rat brain and localization in cholinergic synaptic vesicles

ML Gilmor, NR Nash, A Roghani… - Journal of …, 1996 - Soc Neuroscience
A cholinergic locus has recently been identified consisting of a unique mammalian genomic
arrangement containing the genes for choline acetyltransferase (ChAT) and a putative …

Differences in the developmental expression of the vesicular acetylcholine transporter and choline acetyltransferase in the rat brain

T Hollera, B Berse, JM Cermak, MF Diebler… - Neuroscience …, 1996 - Elsevier
The neurotransmitter acetylcholine (ACh) is synthesized by the enzyme choline
acetyltransferase (ChAT) and then transported into synaptic vesicles by the vesicular …

Coregulation of two embedded gene products, choline acetyltransferase and the vesicular acetylcholine transporter

S Berrard, H Varoqui, R Cervini, M Israël… - Journal of …, 1995 - Wiley Online Library
The gene encoding the vesicular acetylcholine transporter (VAChT) has recently been
localized within the first intron of the gene encoding choline acetyltransferase (ChAT) and is …

Molecular cloning of a putative vesicular transporter for acetylcholine.

A Roghani, J Feldman, SA Kohan… - Proceedings of the …, 1994 - National Acad Sciences
Classical neurotransmitters such as acetylcholine (ACh) require transport into synaptic
vesicles for regulated exocytotic release. The Caenorhabditis elegans gene unc-17 encodes …

Functional identification of a vesicular acetylcholine transporter and its expression from a “cholinergic” gene locus.

JD Erickson, H Varoqui, MK Schäfer, W Modi… - Journal of Biological …, 1994 - ASBMB
The vesicular acetylcholine transporter (VAChT) has been identified and characterized
based on the acquisition of high affinity vesamicol binding and proton-dependent, vesamicol …

Identification and transgenic analysis of a murine promoter that targets cholinergic neuron expression

JM Naciff, MM Behbehani, H Misawa… - Journal of …, 1999 - Wiley Online Library
Choline acetyltransferase (ChAT) is a specific phenotypic marker of cholinergic neurons.
Previous reports showed that different upstream regions of the ChAT gene are necessary for …

Changes of expression levels of choline acetyltransferase and vesicular acetylcholine transporter mRNAs after transection of the hypoglossal nerve in adult rats

J Matsuura, K Ajiki, T Ichikawa, H Misawa - Neuroscience letters, 1997 - Elsevier
Acetylcholine, synthesized in the cytoplasm of cholinergic neurons by choline
acetyltransferase (ChAT), is packaged in synaptic vesicles by vesicular acetylcholine …