Abstract Choline acetyltransferase (CHAT)(EC2. 3.1. 6) is the biosynthetic enzyme for the
neurotransmitter acetylcholine in the central and peripheral nervous systems. In this study, a …

We have isolated recombinant lambda (λ) phages which contain a part of the rat choline
acetyltransferase (ChAT) gene. Restriction and Southern blot analyses using synthetic …

Choline acetyltransferase (ChAT; acetyl‐CoA: cho‐line‐O‐acetyltransferase; EC 2.3. 1.6) is
the enzyme responsible for the synthesis of the neurotransmitter acetylcholine and is thus …

Choline acetyltransferase (ChAT) is specifically expressed in Cholinergic neurons. To
identify control mechanisms regulating the cell‐specific expression of the gene encoding …

In cholinergic neurons, a specific requirement for precursor choline in the biosynthesis of
acetylcholine (ACh) is thought to be sustained by a presynaptic, hemicholinium-3 (HC-3) …

Vesicular transport proteins package classical neurotransmitters for regulated exocytotic
release, and localize to at least two distinct types of secretory vesicles. In PC12 cells, the …

Descriptive studies have delineated a developmental change in neurotransmitter phenotype
from noradrenergic to cholinergic in the sympathetic innervation of sweat glands in rodent …

Cholinergic nerves are identified by labelling molecules in the ACh synthesis, release and
destruction pathway. Recently, antibodies against another molecule in this pathway have …

Presynaptic synthesis of acetylcholine (ACh) requires a steady supply of choline, acquired
by a plasma membrane, hemicholinium-3-sensitive (HC-3) choline transporter (CHT). A …

In Saccharomyces cerevisiae, choline enters the cell via a single high-affinity transporter,
Hnm1p. hnm1 Δ cells lacking HNM1 gene are viable. However, they are unable to transport …