Osteochondral junction is a functional unit comprising the articular cartilage, calcified
cartilage, and subchondral bone. Alteration in any component of this composite unit can …

Osteoarthritis (OA) is a common debilitating joint disorder, affecting large sections of the
population with significant disability and impaired quality of life. During OA, functional units …

Osteoarthritis (OA) is a long-term condition that causes joint pain and reduced movement.
Notably, the same pathways governing cell growth, death, and differentiation during the …

Aims Osteoarthritis (OA) is a common degenerative joint disease worldwide, which is
characterized by articular cartilage lesions. With more understanding of the disease, OA is …

Although cartilage degradation is the characteristic feature of osteoarthritis (OA), it is now
recognized that the whole joint is involved in the progression of OA. In particular, the …

Cartilage and the bordering subchondral bone form a functionally active regulatory interface
with a prominent role in osteoarthritis pathways. The Wnt and the OPG-RANKL-RANK …

This year in review on osteoarthritis biology summarizes a series of research articles
published between the 2020 and 2021 Osteoarthritis Research Society International …

Osteoarthritis (OA) is the most common degenerative joint disease and a major cause of
pain and disability in adult individuals. The etiology of OA includes joint injury, obesity …

Currently, osteoarthritis (OA) is considered a disease of the entire joint, which is not simply a
process of wear and tear but rather abnormal remodelling and joint failure of an organ. The …

Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …