The purpose of this review was to present highlights from the published literature on the
topic of the biology of osteoarthritis (OA). A PubMed search was conducted in order to locate …

Osteoarthritis (OA) is the most common chronic joint disorder worldwide, with a high
personal burden for the patients and an important socio-economic impact. Current therapies …

Osteoarthritis (OA) is a major cause of pain and disability in the aging population, but its
pathogenesis remains incompletely understood. Alterations beneath the articular cartilage at …

The spectrum of arthritis ranges from erosive (eg, rheumatoid arthritis) to ossifying disease
with formation of new bone (eg, ankylosing spondylitis and osteoarthritis). The molecular …

Osteoarthritis (OA) is a degenerative joint disease that is characterized primarily by
progressive breakdown of articular cartilage. The loss of proteoglycans, the mineralization of …

Osteoarthritis is the most common degenerative musculoskeletal disease. In healthy
cartilage, a low turnover of extracellular matrix molecules occurs. Proper balance of anabolic …

The phenotypic change of chondrocytes and the interplay between cartilage and
subchondral bone in osteoarthritis (OA) has received much attention. Structural changes …

Osteoarthritis (OA) is mainly caused by ageing, strain, trauma, and congenital joint
abnormalities, resulting in articular cartilage degeneration. During the pathogenesis of OA …

Osteoarthritis comprises several joint disorders characterized by articular cartilage
degeneration and persistent pain, causing disability and economic burden. The incidence of …

Osteoarthritis (OA) is a chronic degenerative change with high incidence and leads to a
lower quality of life and a larger socioeconomic burden. This study aimed to explore …