Inflammatory and metabolic signaling interfaces of the hypertrophic and senescent chondrocyte phenotypes associated with osteoarthritis

E Horváth, Á Sólyom, J Székely, EE Nagy… - International Journal of …, 2023 - mdpi.com
Osteoarthritis (OA) is a complex disease of whole joints with progressive cartilage matrix
degradation and chondrocyte transformation. The inflammatory features of OA are reflected …

WNT signaling and chondrocytes: from cell fate determination to osteoarthritis physiopathology

N Sassi, L Laadhar, M Allouche, A Achek… - Journal of Receptors …, 2014 - Taylor & Francis
Context: Osteoarthritis (OA) is an articular disorder leading to the degradation of articular
cartilage phenotypical chondrocytes modifications, including the acquisition of a fibroblast …

[HTML][HTML] Osteoarthritis year in review 2020: biology

MHJ van den Bosch - Osteoarthritis and cartilage, 2021 - Elsevier
This year in review about osteoarthritis biology highlights a selection of articles published
between the 2019 and 2020 Osteoarthritis Research Society International (OARSI) World …

[HTML][HTML] Osteoarthritis year in review 2017: biology

CT Appleton - Osteoarthritis and cartilage, 2018 - Elsevier
Summary This Year in Review was derived from a personal selection of articles investigating
biological mechanisms of osteoarthritis (OA) and presented at the OARSI World Congress …

Is osteoarthritis a disease involving only cartilage or other articular tissues?

J Martel-Pelletier, JP Pelletier - Eklem hastaliklari ve cerrahisi= Joint …, 2010 - europepmc.org
Osteoarthritis (OA) is a progressive and disabling disease resulting from a combination of
risk factors, including advancing age, genetics, trauma, knee malalignment, increased …

Interplay of inflammatory mediators with epigenetics and cartilage modifications in osteoarthritis

S Raman, U FitzGerald, JM Murphy - Frontiers in Bioengineering and …, 2018 - frontiersin.org
Osteoarthritis (OA), a degenerative disease of diarthrodial joints, is influenced by
mechanical and inflammatory factors with aging, obesity, chronic injuries, and secondary …

New findings in osteoarthritis pathogenesis: therapeutic implications

L Pulsatelli, O Addimanda, V Brusi… - … in Chronic Disease, 2013 - journals.sagepub.com
This review focuses on the new perspectives which can provide insight into the crucial
pathways that drive cartilage-bone physiopathology. In particular, we discuss the critical …

Cell interplay in osteoarthritis

Z Li, Z Huang, L Bai - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Osteoarthritis (OA) is a common chronic disease and a significant health concern that needs
to be urgently solved. OA affects the cartilage and entire joint tissues, including the …

Pathological mechanism of chondrocytes and the surrounding environment during osteoarthritis of temporomandibular joint

B Li, G Guan, L Mei, K Jiao, H Li - Journal of cellular and …, 2021 - Wiley Online Library
Temporomandibular joint (TMJ) osteoarthritis is a common chronic degenerative disease of
the TMJ. In order to explore its aetiology and pathological mechanism, many animal models …

[HTML][HTML] Osteoarthritis year in review 2018: biology

J Sherwood - Osteoarthritis and cartilage, 2019 - Elsevier
Summary This Year in Review highlights a selection of articles published between the 2017
and 2018 Osteoarthritis Research Society International (OARSI) World Congress meetings …